Facilities
Macquarie University Advanced Spectroscopy Centre (MUASC)
Macquarie University Advanced Spectroscopy Centre (MUASC) is a service and research facility which provides state-of-the-art spectroscopic tools and expertise for molecular characterization, protein chemistry, biophysics and material sciences.
- The facility centre comprises a series of vibrational spectroscopy techniques such as:
- FT-IR,
- Portable Raman
- Raman Optical Activity
- Confocal Raman+AFM (TERS)
- Vibrational circular dichroism
- Electronic spectroscopy (UV-Visible, NIR and fluorescence, circular dichroism) and linear spectroscopy (linear dichroism)
- Light scattering (dynamic light scattering, nanoparticle tracking analysis)
- Nuclear magnetic resonance spectroscopy (600 MHz, 500 MHz and 400 MHz)
Instrumentation EV (extracellular vesicles) analysis facility
Optima MAX-XP Ultracentrifuge: The Optima MAX-XP Ultracentrifuge is used for isolating EVs (e.g., exosomes) from biofluids through differential or density gradient centrifugation. It's a common tool for EV purification.
Automatic Fraction Collector (AFC): qEV columns (size exclusion chromatography (SEC)) are recognised by an AFC and AFC precisely measures fractions by weighing every drop, separating EVs based on size for isolation and purification.
Exodus H600: Automatic Systems for EV isolation powered by ultrasonic nano-filtration technology, combining negative pressure oscillation (NPO) with double-coupled ultrasonic harmonic oscillation to isolate ultra-pure EVs.
NanoFCM: NanoFCM enables single-particle analysis of EVs via flow cytometry, characterizing EV populations including particle size distribution, particle concentration, and surface markers (one green channel, one red channel).
Nanosight NS300: Nanosight measures EV size distribution and concentration in samples using nanoparticle tracking analysis, providing valuable data on EV populations.
Instrumentation
View our full list of instruments.
Our services
Our services are used in wide range of applications from characterising paint chips to measuring trace metals in water to identifying protein structure. It also facilitates collaborations across internal and external research groups, and bridges the knowledge gap between academia and industry needs, enabling commercial translation of basic research into industry.
We have strong connections with ARC CNBP, ARC ITTC-FAAB, MQ Photonics Research centre and MQ Biomolecular Discovery Research Centre.