Our projects
Areas of Interest and Research Focus
Our key areas of interest are Computational Structural Biology, Sequence Variations, Biodiversity Informatics, Cheminformatics, Drug Designing and Mass Spectrometry Data Analysis
Computational Structural Biology
- Applying computational methods to identify potential T cell epitopes for vaccine design
- Mapping disease causing mutations (especially in human) to protein structures for genotype-phenotype correlations
- Identifying the characteristics for structural domain interfaces to predict potential protein interactions
Variations at Genome, Transcriptome and Proteome Levels
- Alternative splicing events by whole genome comparisons
- Characterizing background variations from deleterious changes
- Biomarkers discovery from a Boolean based integrated approach
Computer-Aided Drug Designing
- Identification of novel and more potent lead compounds against disease targets
- Application of molecular dynamics simulation and docking strategies to study potential drug-receptor interactions
- Characterization of protein structural modifications using advanced computational techniques
Biodiversity Informatics and Cheminformatics
- Australian aboriginal medicinal plant relevance and distribution
- Bioactive characterization
- Cheminformatics studies of drugs, toxins and metabolites for predicting novel therapeutics