Our projects

Our projects

Areas of Interest and Research Focus

Our key areas of interest are Computational Structural Biology, Sequence Variations, Biodiversity Informatics, Cheminformatics, Drug Designing and Mass Spectrometry Data Analysis

Computational Structural Biology

  • Applying computational methods to identify potential T cell epitopes for vaccine design
  • Mapping disease causing mutations (especially in human) to protein structures for genotype-phenotype correlations
  • Identifying the characteristics for structural domain interfaces to predict potential protein interactions

Variations at Genome, Transcriptome and Proteome Levels

  • Alternative splicing events by whole genome comparisons
  • Characterizing background variations from deleterious changes
  • Biomarkers discovery from a Boolean based integrated approach

Computer-Aided Drug Designing

  • Identification of novel and more potent lead compounds against disease targets
  • Application of molecular dynamics simulation and docking strategies to study potential drug-receptor interactions
  • Characterization of protein structural modifications using advanced computational techniques

Biodiversity Informatics and Cheminformatics

  • Australian aboriginal medicinal plant relevance and distribution
  • Bioactive characterization
  • Cheminformatics studies of drugs, toxins and metabolites for predicting novel therapeutics
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