Biophysical Chemistry Research Group
We study the structure of biomacromolecules and how they interact with their molecular environment to determine how they function in the molecular assemblies found in cells. We have a range of projects involving DNAs, proteins (globular, membrane and fibrous), membrane bilayers, and glycan structures.
The key feature of our laboratory is a suite of polarised light spectrometers. Our special expertise is with circular and linear dichroism spectroscopies and their application to solve biomolecule problems. Our work involves application of existing techniques and development of new ones to solve problems. We have electronic and vibrational absorbance, circular dichroism, and linear dichroism; Raman and Raman optical activity; fluorescence; dynamic light scattering; atomic force microscopy; a 7-figure balance; a plasma asher; and an enthusiasm to collaborate on projects involving interesting molecular systems.