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Professor Tristan Yan

Cardiovascular and Thoracic Surgery

Contact Details

Tel: 02 9850 2779


Level 1, 75 Talavera St, Macquarie University

Professor Tristan Yan is a Consultant Cardiothoracic Surgeon, Professor of Cardiovascular and Thoracic Surgery at the Macquarie University Hospital and Associate Clinical Professor at the University of Sydney, Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital in Sydney, Australia. He was trained at Royal Prince Alfred Hospital and St Vincent’s Hospital in Sydney and then obtained a Cardiothoracic Surgery Fellowship from the Royal Australasian College of Surgeons. Following advanced specialty fellowships in the United States, England, Scotland and Germany, he is fully trained in major thoracic aortic surgery, minimally invasive cardiac surgery, and minimally invasive thoracic surgery. Professor Yan’s research involvement and leadership extends to international projects. He is the Chairman of CORE Group International, and responsible for establishing and organizing the world’s largest multi-institutional Aortic ARCH Registry, consisting of more than 12,000 patients. He is also the founder and the Editor-in-Chief of the Annals of Cardiothoracic Surgery.


BSc, MBBS (University of New South Wales), MS (University of Sydney), MD (University of New South
Wales), PhD (University of New South Wales) FRACS

Research Interests 

Professor Tristan Yan is dedicated to surgical innovations. He applies the latest pioneering techniques to minimize surgical trauma and access sites and thus achieves a more rapid and comfortable recovery for his patients. Professor Yan has surgical expertise and specialised research interests in minimally invasive cardiac surgery, minimally invasive thoracic surgery and major thoracic aortic surgery.

Specific research interests include:

  • Aortic Arch Surgery
    Aortic arch surgery remains one of the most challenging operations conducted by cardiothoracic surgeons.  Evolving surgical techniques within the past decade has renewed interest in understanding neuroprotection strategies and endovascular devices and placements.  This project aims to allow the scholar to investigate, both through the literature, international databases, and laboratory models, the optimal surgical techniques to improve patient outcomes following aortic arch surgery.
  • Video Assisted Thoracoscopic Surgery
    Lung cancer remains the most common cause of cancer related deaths today. With improved imaging modalities and increased screening programs, more patients are diagnosed with early-stage non-small cell lung cancer (NSCLC) than ever before. For eligible patients with early stage peripheral lesions, intervention may be performed through lobectomy or sublobar resection via video assisted thoracoscopic surgery (VATS).  VATS lobectomy procedures for NSCLC was first described in the early 1990s. With advancements in thoracoscopic instrumentation and technical development, the VATS approach has revolutionized modern thoracic surgical practice and significantly improved patient outcomes. This study aims to further define the role of VATS lobectomy for NSCLC and to identify the optimal surgical treatment strategy for patients with early-stage peripheral NSCLC.
  • Minimally Invasive Cardiac Surgery
    Minimally invasive cardiothoracic surgery has increasingly gained acceptance in the surgical realm, with the aim of achieving equivalent or superior outcomes compared to conventional open sternotomy approaches.  Minimally invasive heart surgery can be achieved utilizing videoscopic or robotic assistance to allow better visualization and precise tissue handling. Encouraging institutional reports of surgical efficacy, reduced trauma, shorter hospitalization and improved cosmesis have increased the use of the minimally invasive approach in recent years. However, the current evidence is limited by small, underpowered studies and the lack of standardized definitions and reporting criteria. There is also a lack of robust clinical data on newer approaches including sutureless implantation technique for aortic valve replacement, and videoscopic surgical ablation for atrial fibrillation. This project aims to provide the highest quality evidence available to evaluate minimally invasive cardiac surgery techniques and establish standardized definitions, reporting criteria and clinical consensus.
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