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Albert Lee

Research Fellow, Biomedical Sciences

Faculty of Medicine and Health Sciences

Contact Details

Tel: (02) 9850 2777


Level 1, 75 Talavera Rd, Macquarie University

Albert Lee's research interests focus on understanding the mechanisms of cellular survival upon stress, and its role in biological processes that manifest into human diseases such as neurological disorders. His research uses proteomics to characterise post-translational modifications (including phosphorylation, ubiquitination, and glycosylation) to understand their role in cellular processes.


B.Sc (Usyd), M.Sc (Macquarie), Ph.D (Macquarie)

Research Interests 

 Motor neurone disease, cellular stress, post-translational modifications, proteomics, signalling

Select Publications 

  1. Zhong, J., Martinez, M, Sengupta S, Lee A,…, Zachara NE. Quantitative phosphoproteomics reveals crosstalk between phosphorylation and O-GlcNAc in the DNA damage response pathway. Proteomics. 2015. 15(2-3):591-607
  2. Reeves R.A, Lee A, Hart G.W, Zachara, N.E. Characterization of the Specificity of CTD110.6, an O-GlcNAc reactive antibody under conditions of starvation and stress. Analytical Biochemistry. 2014. 457: 8-18
  3. Groves J.A.*; Lee A*; Yildirir G.; Zachara N.E., Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis. Cell Stress and Chaperones. 2013. 18(5):535-58
  4. Lee, A.; Chick, J. M.; … Baker, M. S., Liver membrane proteome glycosylation changes in mice bearing an extra-hepatic tumour. Mol Cell Proteomics 2011. doi: 10.1074/mcp.M900538-MCP200
  5. Neilson, K.A.; Ali N.A.; Muralidharan, S.; Mirzaei, M.; Mariani, M.; Assadourian, G.; Lee, A.; van Sluyter, S.C.; Haynes, P.A. Less label, more free: Approaches in label-free quantitative mass spectrometry. Proteomics 2011. 11: 535-553

Research Grants 

Motor Neurone Disease Research Institute Australia (MNDRIA) Grant-in-Aid ($98,150)

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