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Nicholas Cole

Senior Lecturer and Group Leader

Biomedical Sciences, Faculty of Medicine and Health Sciences

Contact Details

Tel: (02) 9850 2740


Level 1, 75 Talavera Road, Macquarie University

B.Sc. University of Liverpool. PhD. St Andrews University, UK. First post-doctorate, Dundee University. Second post-doctorate, The Victor Chang Cardiac Research Institute, Sydney. Lectureship, The University of Sydney. Senior Lectureship, Macquarie University, Sydney.


B.Sc. Hons. PhD

Research Interest

  • Motor Neurone Disease (MND)/Amyotrophic Lateral Sclerosis (ALS)
  • Frontotemporal dementia (FTD)
  • Neurodegenerative Disease
  • Development
  • Zebrafish

Select Publications

  1. Morsch, M., Radford, R., Lee, A., Don, E.K., Badrock, A.P., Hall, T.E., Cole, N.J., and Chung, R. (2015). In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord. Frontiers in cellular neuroscience 9, 321
  2. Nguyen, P.D., Hollway, G.E., Sonntag, C., Miles, L.B., Hall, T.E., Berger, S., Fernandez, K.J., Gurevich, D.B., Cole, N.J., Alaei, S., et al. (2014). Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1. Nature 512, 314-318.
  3. Acosta, J.R., Goldsbury, C., Winnick, C., Badrock, A.P., T., F.S., S., L.A., E., H.T., K., D.E., A., F.J., P., B.I., et al. (2014). Mutant human FUS is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells. Plos One
  4. Don, E.K., Currie, P.D., and Cole, N.J. (2013). The evolutionary history of the development of the pelvic fin/hindlimb. Journal of Anatomy 222, 114-133
  5. Cole, N.J., and Currie, P. (2012). Shaping muscle bioarchitecture for the fin to limb transition. Bioarchitecture 2, 98-103.
  6. Cole, N.J., Hall, T.E., Don, E.K., Berger, S., Boisvert, C.A., Neyt, C., Ericsson, R., Joss, J., Gurevich, D.B., and Currie, P.D. (2011). Development and Evolution of the Muscles of the Pelvic Fin. Plos Biology 9
  7. Hollway, G.E., Bryson-Richardson, R.J., Berger, S., Cole, N.J., Hall, T.E., and Currie, P.D. (2007). Whole-somite rotation generates muscle progenitor cell compartments in the developing zebrafish embryo. Developmental Cell 12, 207-219.
  8. Cole, N.J., Tanaka, M., Prescott, A., and Tickle, C. (2003). Expression of limb initiation genes and clues to the morphological diversification of threespine stickleback. Current Biology 13, R951-R952.

Grant Success

  • Dementia research Teams Grant (NHMRC), 2015-2020 $6,377,279. Developing insight into the molecular origins of familial and sporadic frontotemporal dementia. APP1095215.
  • Project Grant NHMRC 2015-2018 $676,000. Disruption to intracellular trafficking as a central pathogenic mechanism in amyotrophic lateral sclerosis (ALS). APP1086887
  • ARC Project Grant. 2014-2017 $383,000 Visualising neuron-glia interactions in the injured central nervous system. DP140103233
  • Project Grant NHMRC 2012-2015, $435,000 Investigating the pathogenesis of Motor Neurone Disease using zebrafish models. APP1034816
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