Faculty of Medicine & Health Sciences: Biomedical Sciences - Technology platform for noninvasive measurement of intracranial pressure
Technology platform for noninvasive measurement of intracranial pressure
The project aims to develop technology for
noninvasive measurement of fluid pressure in the brain. Engineering approaches
will aim to characterise relationships between arterial and intracranial
pressure from experimental data, computational models and signal processing of
noninvasive blood pressure in the aorta, pressure in the eye and blood flow in
brain and retinal vessels. Findings are expected to produce novel engineering
advances in development of techniques and devices for intracranial pressure
measurement, a procedure currently limited to high-risk invasive methods. This
technology is anticipated to enable measurement of intracranial pressure in
non-acute screening procedures for improved assessment of brain function.
The candidate will be expected to have a solid grounding in basic circulatory physiology and experience in signal processing. The project will involve laboratory experiments in rats to measure arterial and intracranial pressure with fluid interventions to alter cerebral tissue compliance. System identification techniques will be applied to estimate models parameters. Data will also be collected from human subjects with indwelling intracranial catheters together with transcranial blood flow measurements. There will be substantial interaction with the collaborative industrial partner to implement the existing technology of obtaining the central aortic pressure waveform from the peripheral arterial pulse and applying this to obtain a continuous calibrated intracranial pressure waveform.
Professor Alberto Avolio
+61 2 9850 2747
This scholarship is available to eligible candidates to undertake either:
- Research Training Pathway (RTP) MRes Year 2 followed by a possible Macquarie University Research Training Program scholarship (MQRTP) for a 3 year PhD. This is referred to as an MRes/PhD ‘bundle offer’. MRES Year 2, Semester 2 commencement is subject to further approval;
- Direct entry into a 3 year PhD program.
The value and tenure of the scholarship/s is/are:
- The MRES Year 2 full-time stipend rate is $26 288 per annum (2016 rate) tax exempt
- The MQRTP full-time stipend rate is $26,288 per annum (in 2016 tax exempt, for up to 3 years (indexed annually)
For international candidates, the scholarship includes Macquarie University tuition fees for up to three years/four years
Applicants will need to Apply for a research degree and scholarship at
arrange for two academic referee reports to be submitted to the Higher Degree
The form can be downloaded from the Forms page.
To be eligible for a scholarship, applicants are expected to have a
record of excellent academic performance and preferably, additional relevant
research experience and/or peer-reviewed research activity, awards and/or
prizes in line with the University’s scholarship rating guidelines.
Refer to the Rating Scholarship Applicants section for more information about these guidelines.
Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer. Please quote the scholarship code on your application.