Intelligent nanoparticles: interactive tools to decode brain activity

Intelligent nanoparticles: interactive tools to decode brain activity


Science and Engineering

Project Name

Intelligent nanoparticles: interactive tools to decode brain activity

Project Description

Understanding how the brain works is one of the greatest challenges in modern science. This project seeks to create a suite of designer nanoparticles and integrated nanoparticle devices capable of real-time sensing of small analytes and adaptive responses With their capacity for real time sensing and precise drug delivery in complex biological samples, they will address the challenges of the current molecular diagnostic technology. They will be able to selectively perform their actions in a functionally heterogeneous mixture of different cell types communicating via secreted products (signalling molecules, neurotransmitters, exosomes etc). They will expose previously unmeasurable cellular events and help to establish their physiological effects. Eventually, these intelligent nanoparticles will be integrated to the device for in vivo diagnosis and therapy. This will lead to revolutionary insights into the complex dynamics in the living brain and transform leading edge in neuroscience and analytical chemistry. Applicable in vitro and in vivo, this novel approach responds to the key research challenge of our times, the understanding of brain activity. Broad national and international collaborations and industry partnerships will amplify the project impact.

Other important information:  Looking for candidates who have the background of nanotechnology, biosensors, neuroscience or microfluidics, et al.


Associate Professor Guozhen Liu
+61 2 9850 8302

This scholarship is available to eligible candidates to undertake either a direct entry 3 year PhD program or a Master of Research Year2 + PhD program.

The value and tenure of the scholarship is:

  • The MQRTP full-time stipend rate is $27,082 per annum (in 2018 tax exempt for up to 4 years (indexed annually)
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the  Rating Scholarship Applicants  section for more information about these guidelines. Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number on your application.

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