High-speed OSAM scanning microscopy for early diagnosis

Excellence in Higher Degree Research – Science & Engineering – 2013 Research Award Winners

Yiqing Lu, Faculty of Science

Practical methods capable of detecting traces of pathogens and/or disease biomarkers are increasingly in high demand. However, existing optical sensing approaches, usually based on colour discrimination, have either limited sensitivity or unacceptable processing speed. 

Lu’s PhD research has broken through the current bio-sensing constraints through his invention of a time-resolved approach called OSAM, an Orthogonal Scanning Automated Microscopy suitable for rapid detection of single cells.

OSAM can also simultaneously detect thousands of species to decode the molecular signatures of individual patients, offering a powerful platform to detect diseases and contamination in early stages.

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