Corticosteroid nasal irrigations after endoscopic sinus surgery for recalcitrant chronic rhinosinusitis

2013 Research Award Highly Commended

Dr Kornkiat Snidvongs, Australian School of Advanced Medicine

Although having strong anti-inflammatory effects, steroid sprays provide poor sinus delivery for treating recalcitrant chronic rhinosinusitis (CRS).

A new treatment of corticosteroid nasal irrigations after endoscopic sinus surgery that combines the therapeutic effects of sinus surgery with the effective delivery of corticosteroid is proposed.

In this treatment paradigm, the purpose of sinus surgery is to create access for topical therapies rather than relieving obstruction.

High-volume and positive pressure irrigations allow pharmaceutical preparations to better contact sinus mucosa and enhance the mechanical removal of mucus and inflammatory products. When recalcitrant CRS is managed with effectively delivered pharmaceutical solutions, therapy is greatly optimised.

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