Associate Professor Julie Atkin

Associate Professor Julie AtkinAssociate Professor of Neurochemistry and Cell Biology

BSc(Hons)(Manchester UK), PhD (Sheffield UK)

Contact Details

Tel: +61 (0)2 9850 2772
Email: julie.atkin@mq.edu.au

 

Professional Overview

A/Prof Atkin is internationally recognised as a leader in the role of cellular stress responses in motor neuron disease (MND).  Her research has opened up promising novel therapeutic targets which she is investigating further.  A/Prof Atkin previously led the MND group at the Florey Neuroscience Institute and in September 2009 she established her own laboratory at the La Trobe Institute for Molecular Science, the only university in Australia to receive the top score of five in both 2011 and 2012 in Research for Australia (ERA) ratings for Biochemistry & Cell Biology. A/Prof Atkin was recently recruited to Macquarie University, Sydney, to the Motor Neuron Disease Research Centre to work alongside other prominent ALS researchers including A/Prof Ian Blair, Prof Roger Chung and Prof Gilles Guillieum. She has also established a strong network of national and international collaborators which will facilitate productive research.  A/Prof Atkin has received over $2.3 million in competitive grant funding during the last ten years and has over 43 publications.   

Current Research Projects

  1. The role of intracellular trafficking as a novel pathogenic mechanism in Amyotrophic Lateral Sclerosis (ALS)/Motor Neuron Disease (MND).
  2. The role of C9ORF72 in Amyotrophic Lateral Sclerosis (ALS)/Motor Neuron Disease (MND).

Research Grant Funding

A/Prof Atkin has demonstrated the ability to consistently attract significant funding from national and international organisations for her research. She has been awarded $2.7 million in total in nationally and internationally competitive research grant funding, with 24 successful applications as lead researcher. This includes; (1) NHMRC: 3 three-year NHMRC Project grants, all as CIA (2) Fellowship: MND Research Institute of Australia Fellowship (3) International: an ALSA (American ALS Association) grant (4) National: many national grants from funding bodies including the MNDRIA, the Brain Foundation and the Bethlehem Griffiths Research Foundation.

Five Select Research Publications

  1. Walker AW, Farg MA, Bye CA, McLean C, Horne MK, Atkin JD "PDI is S-nitrosylated and neuroprotective in ALS" Brain 133:105-116 (2010) (IF= 9.6).
  2. M A Farg, K Y Soo, A K Walker, H Pham, J Orian, 1 M K Horne, S T Warraich, K L Williams, I P Blair, J D Atkin "Mutant FUS induces Endoplasmic Reticulum Stress in ALS and interacts with PDI " Neurobiol of Aging, 33, 2855-2868 (2012) (IF=6.5).
  3. Farg MA, Soo KY, Warraich TS, Sundarmoorthy V, Blair I P, Atkin J D "Ataxin 2 Interacts with FUS and Intermediate Length Polyglutamine Expansions Increase FUS-mediated Toxicity in ALS" Hum. Mol. Genetics 22 (4) 479, 717-728 (2013) (IF=7.6).
  4. Sundaramoorthy, V, Walker, AK, Yerbury, J, Soo, KY, Farg, M A, Hoang, V, Zeineddine, R, Atkin, JD. "Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of ALS in neuronal cells" Cell. Mol. Life Sci.70 (21):4181-95, (2013) (IF=5.8).
  5. M A Farg, V Sundaramoorthy, J M Sultana, S Yang, R A. K. Atkinson , V Levina, M A Halloran, P Gleeson, I P Blair, K Y Soo, A E King, J D Atkin "C9ORF72, implicated in ALS and FTD, regulates endosomal trafficking" Hum Mol Genet (2014, IF=7.6).