Messerle research group

Messerle research group

L to R: Roy, Ashwin, Ralph, Nick, Josh, Barbara, Andrew, Sam, Shelly, Danfeng, Mark. Missing: Matt, IndrekResearch in our group involves organometallic and inorganic synthesis and catalysis, with a particular emphasis upon designing transition metal catalysts for efficient organic transformations (synthetic/industrial catalysis and green chemistry).

Our work relies on the chemistry of multidentate ligand systems, bearing mixed (P, N, C and S) donor atoms. We use a range of techniques including multinuclear NMR spectroscopy, IR, UV-Vis spectroscopy, mass spectrometry and X-ray diffraction for molecular structure determination and mechanistic investigation.

We are always looking for talented individuals to join our group, PhD and post-doc applications are welcomed. Please contact: barbara.messerle@mq.edu.au and roy.mcburney@mq.edu.au

Our research

Organometallics and catalysis

Research in our group involves organometallic synthesis, catalysis, computational molecular modelling and advanced NMR Spectroscopy. Our overall goal is to create highly active catalysts that promote atom-efficient organic transformations. We target key organic transformations that can simultaneously expedite the preparation of high value fine chemicals and at the same time reduce energy consumption and waste We are particularly interested in the synthesis of heterocycles and the development of tandem reactions that facilitate multiple chemical transformations in the same flask.


Catalysing single and multistep reactions

Scheme 2: Examples of tandem reactions.The synthesis of pharmaceuticals relies on the stepwise formation of multiple bonds. Promoting multistep reactions in a single reaction vessel is highly desirable as it reduces the energy required and number of by-products formed. We are developing mono-metallic as well as multimetallic catalysts that mediate two or more sequential reaction steps.[10],[11] These reactions provide efficient routes to the synthesis of oxygen and nitrogen containing heterocycles.

C-X bond formation: The metal catalysed addition of X-H bonds, X = N (hydroamination),[12],[13] O (hydroalkoxylation) [14] and S (hydrothiolation), [15],[16] to alkynes and alkenes is a direct method for the synthesis of C-N, C-O and C-S bonds, and is important in the synthesis of pharmaceuticals as well as new materials and fine chemicals.

Reduction of imines and alcoholysis of silanes: Silyl ethers are among the most widely used protecting groups for the hydroxyl functionality in organic synthesis, and also play an important role in inorganic synthesis as precursors in the preparation of sol-gels and other condensed siloxane materials.

Our iridium complexes with N donor ligands catalyze the alcoholysis of hydrosilanes under mild conditions with extremely high levels of efficiency.[17] The reduction of imines leads to the formation of the all important amines, and is effectively catalysed by our catalysts.

Two step reactions By catalysing C-X bond formation reactions followed by C-C bond formation,  imine reduction or hydrosilation of imines, we are able to efficiently promote tandem reactions, or multistep reactions in a single pot (Scheme 2). This enables the synthesis of more complex organic targets.


Multimetallic Catalysts for Enhanced Reactivity

Scheme 1. Rate enhancements through metal ion cooperativity.Bimetallic complexes are important homogeneous catalysts as the immobilization of two metal centres in close proximity can lead to cooperative effects between the metal centres, so that the resulting catalysts have exceptional efficiency and selectivity.

We have shown a direct correlation between bimetallic catalyst structure and catalyst efficiency.[6] We develop new scaffolds and catalysts for promoting the synthesis of heterocycles and are also interested in understanding how these cooperative effects work.[7], [8]


Novel highly active transition metal catalysts

Figure 1. Example of Ir(I) catalystIn collaboration with Prof. Les Field, UNSW, Australia

In order to develop robust and effective late transition metal catalysts it is essential to finely tune the ligands occupying the primary coordination sphere around the active metal ion. To address this goal we have developed new ligand systems for iridium, rhodium ruthenium and iron ions that facilitate a high reaction rate whilst maintaining the structural integrity of the catalyst. Our ligand systems are primarily based on nitrogen donors, including mixed ligand systems containing sp2-nitrogen donors [1], N-heterocyclic carbenes [2] and phosphines.[3], [4] ,[5] These ligands provide a wide range of metal binding strengths for catalyst optimization. (e.g. a bidentate phosphine-pyrazole ligand bound to Ir(I) to form catalyst 1).


Pincer Ligands


Figure 2. Example of a pincer ligandIn collaboration with Prof. Tony Hill, ANU, Canberra, Australia

Pincer ligands have been extensively investigated as chelating agents for TM ions as the co-planar geometry of the resultant complex serves to inhibit deleterious cyclometallation in various catalytic cycles. We are currently working on the development of novel complexes with pincer ligands[9] containing N-heterocyclic carbene donors in collaboration with Professor Anthony Hill (ANU, Canberra, Australia). Together we also seek to develop new classes of catalysts containing ligands based on the unconventional elements boron and silicon.


Catalysts on Surfaces

Figure 5. Anchoring catalysts onto nanocarbon surfaces.In collaboration with Prof Justin Gooding, UNSW

The separation of homogeneous catalysts from products or substrates continues to be a challenge. To overcome this, we are attaching catalysts already developed by our group onto a variety of robust structures and surfaces.[18] The new anchored catalyst systems can be readily separated from reaction mixtures. This will not only allow easy catalyst/product separation, but will also provide a greater control over the nature of catalyst reactivity. The supports themselves can use the electrochemical properties of the catalysts to promote reactivity, or induce high enantioselectivity in asymmetric transformations.


NMR Spectroscopy and Organometallic Reaction Mechanisms

Understanding the mechanism of any transition metal catalysed reaction pathway is a critical part of the design process when developing of new more efficient catalysts. In the Messerle group we use several different tools to gain insight into the mechanism by which our catalysts operate.

Figure 3: Modelling conformational structure in a bimetallic catalyst.

(i) Computational Studies (in collaboration with Prof. Stuart Macgregor, Heriot Watt University, Edinburgh, UK and Prof. Odile Eisenstein (Institut Charles Gerhardt Montpellier, France)).

We use density functional theory (DFT) calculations to model catalysts and reaction intermediates. This allows us to assess the relationship between the geometry of the TM-catalyst/substrate species and the likely reaction pathway.

(ii) Reaction Kinetics: To learn more about the efficacy of our catalysts we routinely use NMR spectroscopy and GC-MS to determine substrate conversion and calculate turn over numbers. This allows us to quantitatively ‘rank’ catalyst performance and, in combination with computational studies, we are then able to further tune our ligand design.

(iii) Para-Hydrogen Enhanced NMR Spectroscopy (in collaboration with Prof. S. B. Duckett, The University of York, UK):

A good understanding of the spatial structure of a catalyst and the mechanism by which it drives a given reaction is essential in order to optimise its performance in a catalytic process. We use NMR spectroscopy to probe the geometry of metal complexes and investigate the mechanism of catalysed reactions. However, catalytically active species are normally present at such low concentrations in a reaction mixture that they are not normally observable by NMR.

The para-hydrogen effect represents one efficient way of achieving signal enhancement. We are collaborating with Professor S. B. Duckett (The University of York, UK) to use the significantly enhanced signals from para-hydrogen to observe low concentration organometallic species in solution and further understand their behaviour.

Publications

2011-Present

  1. Iridium(III ) homo- and heterogeneous catalysed hydrogen borrowing C– N bond formation, Chin M. Wong, Roy T. McBurney, Samantha C. Binding, Matthew B. Peterson, Vinicius R. Gonçales, J. Justin Gooding, Barbara A. Messerle, Green Chemistry2017, DOI: 10.1039/c7gc01007a
  2. Enhancements in Catalytic Reactivity and Selectivity of Homobimetallic Complexes Containing Heteroditopic Ligands, Mark R. D. Gatus, Roy T. McBurney, Mohan Bhadbhade and Barbara A. Messerle, Dalton Transactions, 2017, DOI: 10.1039/C7DT01294B
  3. Synthesis and catalytic activity of nickel(II) complexes containing NCN pincer ligands, Ashwin G. Nair, Roy T. McBurney, Mark R. D. Gatus, D. Barney Walker, Mohan Bhadbhade and Barbara A. Messerle, Journal of Organometallic Chemistry2017, DOI: 10.1016/j.jorganchem.2017.02.025 – Special issue on the topic of “Organometallic Chemistry of Pincer Complexes” in honour of Prof. Gerard van Koten’s 75th birthday.
  4. Ruthenium(II) Complexes of Hemilabile Pincer Ligands: Synthesis and Catalysing the Transfer Hydrogenation of Ketones, Ashwin G. Nair, Roy T. McBurney, D. Barney Walker, Michael J. Page, Mark R. D. Gatus, Mohan Bhadbhade and Barbara A. Messerle, Dalton Transactions, 201645, 14335-14342.
  5. A versatile method for the preparation of carbon-rhodium hybrid catalysts on graphene and carbon black, Chin Min Wong, D. Barney Walker, Alexander H. Soeriyadi, J. Justin Gooding, and Barbara A. Messerle, Chemical Science, 2016, 7, 1996-2004.
  6. Intermolecular Hydroalkoxylation of Terminal Alkynes Catalyzed by a Dipyrrinato Rhodium(I) Complex with Unusual Selectivity, Raphael H. Lam, D. Barney Walker, Matthew H. Tucker, Mark R. D. Gatus, Mohan Bhadbhade, and Barbara A. Messerle, Organometallics, 2015, 34 (17), 4312-4317.
  7. Bimetallic N-Heterocyclic Carbene Rh(I) Complexes: Probing the Cooperative Effect for the Catalyzed Hydroelementation of Alkynes, Vera Diachenko, Michael J. Page, Mark R. D. Gatus, Mohan Bhadbhade, and Barbara A. Messerle, Organometallics, 2015, 34 (18), 45643-4552.
  8. The Advantages of Covalently Attaching Organometallic Catalysts to a Carbon Black Support: Recyclable Rh(I) Complexes That Deliver Enhanced Conversion and Product Selectivity, Andrey Tregubov, D. Barney Walker, Khuong Vuong, Justin Gooding, and Barbara A. Messerle, Dalton Transactions, 201544, 7917-7926. 
  9. A Ruthenium Based Organometallic Complex for Biosensing That Is Both a Stable Redox Label and a Homobifunctional Linker, Yeng Ying Lee, Stephen G. Parker, Abbas Barfidokht, Muhammad Tanzirul Alam, D. Barney Walker, Barbara A. Messerle, and J. Justin Gooding, Electroanalysis, 2015, 27 (5), 1078-1085.
  10. Hemilabile and Bimetallic Coordination in Rh and Ir Complexes of NCN Pincer Ligands, Giulia Mancano, Michael J. Page, Mohan Bhadbhade, and Barbara A. Messerle, Inorganic Chemistry, 2014, 53, 10159-10170.
  11. Solid-State NMR Structure Characterization of a 13CO-Labeled Ir(I) Complex with a P,N-Donor Ligand Including Ultrafast MAS Methods, Andrey A. Tregubov, Rasmus Linser, Khuong Q. Vuong, Aditiya Rawal, John D. Gehman, and Barbara A. Messerle,  Inorganic Chemistry, 2014, 53, 7146-7153.
  12. Ruthenium(II) complexes containing functionalised β-diketonate ligands: developing a ferrocene mimic for biosensing applications, Yeng Y. Lee, D. Barney Walker, Justin J. Gooding, and Barbara A. Messerle, Dalton Transactions, 2014, 43, 12734-12742.
  13. Bi- and tri-metallic Rh and Ir complexes containing click derived bis- and tris-(pyrazolyl-1,2,3-triazolyl) N–N′ donor ligands and their application as catalysts for the dihydroalkoxylation of alkynes, Khuong Vuong, Chin Min-Wong, Mohan Bhadbhade, and Barbara A. Messerle, Dalton Transactions, 2014, 43, 7540-7553.
  14. Rh(I) Complexes Bearing N,N and N,P Ligands Anchored on Glassy Carbon Electrodes: towards Recyclable Hydroamination Catalysts, Andrey A. Tregubov, Khuong Q. Vuong, Erwann Luais, J. Justin Gooding, and Barbara A. Messerle, Journal of the American Chemical Society, 2013, 135, 16429-16437.
  15. Cooperative Catalysis: Large Rate Enhancements with Bimetallic Rhodium Complexes, Sandra W. S. Choy, Michael J. Page, Mohan Bhadbhade, and Barbara A. Messerle, Organometallics, 2013, 32 (17), 4726-4729.
  16. Cationic Rh and Ir complexes containing bidentate Imidazolylidene-1,2,3-triazole donor Ligands: Synthesis and preliminary Catalytic Studies, Khuong Q. Vuong, Marina Timerbulatova, Matthew B. Peterson, Mohan Bhadbhade, and Barbara A. Messerle, Dalton Transactions, 2013, 42, 14298-14308.
  17. Bimetallic Complexes for Enhancing Catalyst Efficiency – Probing the Relationship between Activity and Intermetallic Distance, Marina Timerbulatova, Mark Gatus, Khuong Vuong, Mohan Bhadbhade, Andrés G. Algarra, Stuart A. Macgregor, and Barbara A. Messerle, Organometallics, 2013, 32 (18), 5071-5081.
  18. Directing the Regioselectivity of Rhodium(I) Catalysed Cyclisation of 2-Alkynyl Benzoic Acids, Bradley Y.-W. Man, Astrid Knuhtsen, Michael J. Page, and Barbara A. Messerle, Polyhedron, 2013, 61, 248-252.
  19. Ir(III) Cp* Complexes for the Efficient Hydroamination of Internal Alkynes, Katherine Gray, Michael J. Page, Jörg Wagler, and Barbara A. Messerle, Organometallics, 2013, 31 (17), 6270-6277.
  20. New Rhodium(I) and Iridium(I) Complexes Containing Mixed Pyrazolyl-1,2,3-Triazolyl Ligands as Catalysts for Hydroamination, Carol Hua, Khuong Q. Vuong, Mohan Bhadbhade, and Barbara A. Messerle, Organometallics, 2013, 31 (5),1790-1800.
  21. In situ Catalysts for the Intramolecular Hydroamination of Aminoalkynes – What Ligand Properties Determine Catalyst Activity?, Sarah L. Rumble, Michael J. Page, Leslie D. Field, Barbara A. Messerle, European Journal of Inorganic Chemistry, 2013, 13, 2226-2231.
  22. Catalysed Tandem C-N/C-C Bond Formation for the Synthesis of Tricyclic Indoles using Ir(III) Pyrazolyl-1,2,3-Triazolyl Complexes, Chin-Min Wong, Khuong Q. Vuong, Mark R. D. Gatus, Carol Hua, Mohan Bhadbhade, and Barbara A. Messerle, Organometallics, 201231 (21), 7500-7510.
  23. Cooperativity in Bimetallic Dihydroalkoxylation Catalysts built on Aromatic Scaffolds: Significant Rate Enhancements with a Rigid Anthracene Scaffold, Joanne Hui Hui Ho, Sandra Choy, Stuart Macgregor, and Barbara A. Messerle, Organometallics, 201130 (21), 5978-5984.
  24. Synthesis and Structure of Homo- and Heterobimetallic Rhodium(I) and/or Iridium(I) Complexes of Binucleating Bis(1-pyrazolyl)methane Ligands, Joanne H. H. Ho, Jörg Wagler, Anthony C. Willis, and Barbara A. Messerle, Dalton Transactions, 2011, 40, 11031-11042.
  25. Rhodium(I) complexes bearing tridentate N-donor ligands: – catalytic activity and ligand lability, Bradley Y. W. Man, Mohan Bhadbhade, and Barbara A. Messerle, New Journal of Chemistry, 2011, 35 (8), 1730-1739.
  26. Intramolecular Hydroamination of Aminoalkenes using Rhodium(I) and Iridium(I) Complexes with N, N- and P,N-Donor Ligands, Thi O. Nguyen, Bradley Y.-W. Man, Richard Hodgson, and Barbara A. Messerle, Australian Journal of Chemistry, 2011,64 (6), 741-746. Invited submission to Themed Issue on Women in Chemistry.
  27. Computational Study of the Mechanism of Cyclic Acetal Formation via the Iridium(I)-Catalyzed Double Hydroalkoxylation of 4-Pentyn-1-ol with Methanol, Torstein Fjermestad, Joanne H. H. Ho, Stuart A. Macgregor, Barbara A. Messerle*, and Deniz Tuna, Organometallics, 2011, 30 (3), 618-626.

2006-2010


  1. Pyridine-2,6-bis(thioether) (SNS) Complexes of Ruthenium as Catalysts for Transfer Hydrogenation, Michael J. Page, Jörg Wagler, and Barbara A. Messerle, Organometallics, 2010, 29 (17), 3790-3798.
  2. Improving intramolecular hydroamination Rh(I) and Ir(I) catalysts through targeted ligand modification, Sophie R. Beeren, Serin L. Dabb, Gavin Edwards, Matthew K. Smith, Anthony C. Willis, and Barbara A. Messerle, New Journal of Chemistry, 2010, 34 (6), 1200-1208.
  3. Highly Efficient Dual Metal Catalyzed Intramolecular Dihydroalkoxylation of Alkyne Diols to form Spiroketals, Joanne Hui Hui Ho, Richard Hodgson, Barbara Ann Messerle,* and Jörg Wagler, Dalton Transactions, 2010, 39 (17), 4062-4069.
  4. 3-Mercapto-2,6-pyridinedicarboxylic acid, a small lanthanide-binding tag for protein studies by NMR spectroscopy, Bradley Man, Xun-Cheng Su, Haobo Liang, Shane Simonsen, Thomas Huber, Barbara Messerle, and Gottfried Otting*, Chemistry a European Journal, 2010, 16 (12), 3827-3832.
  5. Intramolecular Hydroamination Catalysed by Ag complexes Stabilised in situ by Bidentate Ligands, Sophie R. Beeren, Serin L. Dabb, and Barbara A. Messerle, Journal of Organometallic Chemistry, 2009694 (2), 309-312.
  6. The mechanism of N-vinylindole formation via tandem imine formation and cycloisomerisation of o-ethynylanilines, Danielle F. Kennedy, Ainara Nova, Anthony C. Willis, Odile Eisenstein*, and Barbara A. Messerle*, Dalton Transactions, 2009, 10296-10304.
  7. Unusual Reactivity of the Bis(pyrazolyl)borate Chelate: B-H for B-X (X= F, Cl and OH) Substitution in Complexes of Ruthenium, Michael J. Page, Barbara A. Messerle,* and Jörg Wagler, Organometallics, 2009, 28, 6145-6151.
  8. Pyrazolyl-N-Heterocyclic Carbene Complexes of Rhodium as Hydrogenation Catalysts: The influence of Ligand Steric Bulk on Catalyst Activity, Michael J. Page, Jörg Wagler, and Barbara A. Messerle*, Dalton Transactions, 2009, 7029-7038.
  9. Rhodium(I) and iridium(I) complexes containing bidentate phosphine-imidazolyl donor ligands as catalysts for the hydroamination and hydrothiolation of alkynes, Leslie D. Field, Barbara A. Messerle,* Khuong Q. Vuong, and Peter Turner, Dalton Transactions, 2009, 3599-3614.
  10. Identification by NMR Spectroscopy of the Two Stereoisomers of the Platinum Complex [PtCl2(S-ahaz)] (S- ahaz = 3(S)-aminohexahydroazepine) Bound to a DNA 14- mer oligonucleotide. NMR Evidence of Structural Alteration of a Platinated A -rich 14-mer DNA Duplex, Connie Diakos, Barbara Messerle, P. Del Murdoch, John Parkinson, Peter Sadler, Ronald Fenton Trevor Hambley*, Inorganic Chemistry, 2009, 48 (7), 818-82.
  11. Intramolecular cyclization of ortho-alkynanalines by Rh(I) catalyzed hydroamination to yield benzo(dipyrroles), Guy K Clentsmith, Leslie D Field,* Barbara A Messerle, Adelle Shasha and Peter Turner, Tetrahedron Letters, 2009, 50 (13),1469-1471.
  12. Application of UV-Vis Spectroscopy to High Throughput Screening of Hydroamination Catalysts, Danielle F. Kennedy, Barbara A. Messerle* and Sarah L. Rumble, New Journal of Chemistry, 2009, 818-824.
  13. Highly efficient catalytic routes to spiroketal motifs, Selvasothi Selvaratnam, Joanne H.H. Ho,Paul B. Huleatt, Barbara A. Messerle,* Christina L. L. Chai,* Tetrahedron Letters, 200950, 1125-1127.
  14. Binding of [Pt(1C3)(dien)]2+ to the duplex DNA oligonucleotide 5′-d(TGGCCA)-3′: the effect of an appended positive charge on the orientation and location of anthraquinone intercalation, Renee M. Whan, Barbara A. Messerle, and Trevor W. Hambley*, Dalton Transactions, 2009, 932-939.
  15. Weakly Coordinating Counter-Ions for Highly Efficient Catalysis of Intramolecular Hydroamination, Serin L. Dabb, Joanne H. H. Ho, Richard Hodgson, Barbara A. Messerle* and Jörg Wagler, Dalton Transactions, 2009, 634-642.
  16. Rh(I) and Ir(I) Catalysed Intermolecular Hydroamination with Substituted Hydrazines, Serin L. Dabb and Barbara A. Messerle, Journal of the Chemical Society, Dalton Transactions, 2008, 6368-6371.
  17. Formation of Metallacyclobutene Complexes via the Addition of Hydrazines to Ruthenium Vinylidene Complexes, Serin L. Dabb, Barbara A. Messerle,* Jörg Wagler, Organometallics, 2008, 27 (18), 4657-4665.
  18. Ruthenium Complexes of Substituted Hydrazine – Novel Solution and Solid State Binding Modes, Serin L. Dabb, Barbara Messerle,* Gottfried Otting, Jörg Wagler, and Anthony Willis, Chemistry a European Journal, 2008, 14 (32), 10058-10065.
  19. A dipicolinic acid tag for rigid lanthanide tagging of proteins and paramagnetic NMR spectroscopy,Xun-Cheng Su, Bradley Man,Sophie Beeren, Haobo Liang, Shane Simonsen, Christophe Schmitz, Thomas Huber, Barbara Messerle, Gottfried Otting*, Journal of the American Chemical Society, 2008, 130, 10486.
  20. High throughput screening arrays of rhodium and iridium complexes as catalysts for intramolecular hydroamination using parallel factor analysis, Diako Ebrahimi, Danielle Kennedy, Barbara Messerle, and D. Brynn Hibbert*, Analyst, 2008, 133 (6), 817-822.
  21. Ru and Os Complexes containing a heterotopic P-N Ligand: The Effect of Solvent on Stereochemistry, Serin L. Dabb, Barbara A. Messerle,* Matthew K. Smith, and Anthony C. Willis, Inorganic Chemistry, 200847 (8), 3034-3044.
  22. Fast capillary electrophoresis for combinatorial catalysis, Michael C Breadmore, Richard Hodgson, Danielle F Kennedy, and Barbara A Messerle Electrophoresis, 2008, 29 (2), 491-498.
  23. Late Transition Metal Catalyzed Intramolecular Hydroamination – The effect of Ligand and Substrate Structure, Suzanne Burling, Leslie D Field, Barbara A. Messerle, and Sarah L. Rumble, Organometallics, 200726, 4335-4343.
  24. Rhodium and Iridium Catalysed Double Hydroalkoxylation of Alkynes, an Efficient Method for the Synthesis of O,O-acetals: Catalytic and Mechanistic Studies, Barbara A. Messerle*, and Khuong Q. Vuong, Organometallics, 200726, 3031-3040.
  25. Rhodium(I) and Iridium(I) Complexes with Bidentate Phosphine-Pyrazolyl Ligands: Highly Efficient Catalysts for the Hydroamination Reaction, Leslie D. Field, Barbara A. Messerle,* Khuong Q. Vuong, Peter Turner, and Tim Failes, Organometallics, 2007, 26, 2058-2069.
  26. Synthesis of Cp* Iridium and Rhodium complexes Containing Bidentate sp2N-Donor Ligands and the Counter-anions [Cp*MCl3], Danielle F. Kennedy, Barbara A. Messerle*,Matthew K. Smith, European Journal of Inorganic Chemistry, 2007, 80-89.
  27. Reactive Indolyl Complexes of Group 9 Metals, Joanne Hui Hui Ho, David St Claire Black, Barbara A. Messerle,* Jack Clegg and Peter Turner, Organometallics, 200624, 5800-5810.
  28. Free Radical Polymerization with Catalytic Chain Transfer: Using NMR to Probe the Strength of the Cobalt-Carbon Bond in Small Molecule Model Reactions, David A. Morrison, Johan P. A. Heuts, Thomas P. Davis,*Barbara Messerle,* Alexei A.. Gridnev, Journal of Polymer Science Part A: Polymer Chemistry, 2006, 44 (21), 6171-6189.
  29. Rhodium(I) and Iridium(I) Complexes of Pyrazolyl-N-Heterocyclic Carbene Ligands, Barbara A. Messerle, Michael J. Page, and Peter Turner, Dalton Transactions, 2006, 3927-3933.
  30. Synthesis of spiroketals by iridium-catalyzed double hydroalkoxylation, Barbara A. Messerle* and Khuong Q. Vuong, Pure and Applied Chemistry, 200678, 197-523.

2001-2005


  1. Intramolecular Hydroamination with Rhodium(I), Iridium(I) Complexes containing a Phosphine, N-Heterocyclic Carbene Ligands, Leslie D. Field, Barbara A. Messerle,* Khuong Q. Vuong, and Peter Turner, Organometallics, 2005, 24, 4241-4250.
  2. Proximity extension of circular DNA aptamers for real-time protein detection, Daniel A. Di Giusto, Wjatschesslaw A. Wlassoff, J. Justin Gooding, Barbara A. Messerle, and Garry C. King,Nucleic Acids Research, 2005, 33, Art. No. e64.
  3. Iridium(I)-Catalysed Tandem Hydrosilylation-Protodesilylation of Imines, L. D. Field, B. A. Messerle,* and S. L. Rumble, European Journal of Organic Chemistry, 2005, 2005 (14), 2881.
  4. An Iron(II) Dihydrogen Hydrido Complex Containing the Tripodal Tetraphosphine Ligand P(CH2CH2PMe2)3, L.D. Field,* H.L. Li, B.A Messerle, R.J. Smernik, and P. Turner, Dalton Transactions, 2004,1418-1423.
  5. Cyclisation of Acetylenic Amides Using a Cationic Rhodium(I) Complex, S. Burling, L. D. Field,* H. L. Li, B. A. Messerle,* and A. Shasha, Australian Journal of Chemistry, 2004, 57, 677-680, special edition in honour of Professor Lew Mander.
  6. Intramolecular Hydroamination Catalysed by Cationic Rhodium and Iridium Complexes with Bidentate Nitrogen-donor Ligands, S. Burling, L. D. Field,* B. A. Messerle,* and P. Turner, Organometallics, 200423, 1714-1721.
  7. One-Pot Tandem Hydroamination/Hydrosilation Catalyzed by Cationic Iridium(I) Complexes, L. D. Field, B. A. Messerle,* and S. L. Wren, Organometallics, 200322, 4393-4395.
  8. Rhodium(I) and Iridium(I) Complexes with Bidentate N,N and P,N Ligands as Catalysts for the Hydrothiolation of Alkynes, S. Burling, L.D. Field, B.A. Messerle,* K.Q. Vuong, and P. Turner, Dalton Transactions, 2003, 21, 4181-4191.
  9. Mononuclear Rhodium(I) Complexes with Chelating N-Heterocyclic Carbene Ligands – Catalytic Activity for Intramolecular Hydroamination, S. Burling, L.D. Field,* H.L. Li, B.A. Messerle, and P. Turner, European Journal of Inorganic Chemistry, 2003, 17, 3179-3184.
  10. Investigations into the interactions between DNA and conformationally constrained pyridylamineplatinum(II) analogues of AMD473, Vivienne P. Munk, Connie I. Diakos, Leanne T. Ellis, Ronald R. Fenton, Barbara A. Messerle and Trevor W. Hambley,* Inorganic Chemistry, 200342, 3582-3590.
  11. Cationic Ir(I) Complexes as Catalysts in the Alcoholysis of Silanes, L.D. Field,* B.A. Messerle,* L.P. Soler, M. Rehr, and T.W. Hambley, Organometallics, 200322, 2387-2395.
  12. Structure and Reactivity of Ruthenium(II) Carbonyl Complexes Containing Bispyrazol-1-ylmethane and Bis(N-methylimidazol-2-yl)methane, Barbara A. Messerle,* Vicki-Anne Tolhurst, and Peter Turner Synthesis, European Journal of Inorganic Chemistry, 2003, 298-300.
  13. Stereospecificity and Enantioselectivity in the Binding of the Platinum(II) Complex [PtCl2(tmdz)] (tmdz = 5,5,7-trimethyl-1,4-diazacycloheptane) to Dinucleotides and Oligonucleotides, Vivienne P. Munk, Barbara A. Messerle, Ronald R. Fenton and Trevor W. Hambley,* Chemistry – A European Journal, 2002, 8, 5486-5493.
  14. Iron (II) Complexes containing Poly(1-pyrazolyl)methane Ligands, L.D. Field,* B.A. Messerle,* L.P. Soler, I. Buys, and T.W. Hambley, Journal of Organometallic Chemistry, 2002, 655, 146-157.
  15. Isomer formation in the binding of [PtCl2(cis-cyclohexane-1,3-diamine)] to oligonucleotides and the X-ray crystal structure of [PtCl2(cis-cyclohexane-1,3-diamine)].dimethylformamide, Tsuey Cham, Connie I. Diakos, Leanne T. Ellis, Ronald R. Fenton, Vivienne P. Munk, Barbara A. Messerle and Trevor W. Hambley,* Dalton Transactions, 2001, 2769-2774.
  16. Structure, Stability and Interconversion Barriers of the Rotamers of cis-[PtIICl2(quinoline)2] and cis-[PtIICl2(3-bromoquinoline)(quinoline)] from X-ray Crystallography, NMR spectroscopy and Molecular Mechanics Evidence, M. Davies, C. Diakos, B.A. Messerle, and T.W. Hambley,* Inorganic Chemistry, 2001, 40, 3048-3054.
  17. Polypyrazolyl Complexes of Ruthenium, L.D. Field,* B.A. Messerle,* L.P. Soler, I.E. Buys, and T.W. Hambley, Dalton Transactions, 2001,1959-1965.

1996-2000


  1. Addition of H2 to a Cationic Iridium(I) Complex: a Series of Reaction Products, S.B. Duckett, L.D. Field, B.A. Messerle,* W.J. Shaw and L.P. Soler, Dalton Transactions, 200014, 2251-2253.
  2. Cyclisation of Acetylenic Carboxylic Acids and Acetylenic Alcohols to Oxygen-containing Heterocycles using Cationic Rhodium(I) Complexes, Sarah Elgafi, Leslie D. Field,* and Barbara A. Messerle,* Journal of Organometallic Chemistry, 2000, 607, 97-104.
  3. Hydroamination of alkynes catalysed by a cationic rhodium complex, Suzanne Burling, Leslie D. Field,* and Barbara A. Messerle,* Organometallics, 2000, 19, 87-90.
  4. Butenynyl Complexes of Iron(II) Containing the Tripodal Tetraphosphine Ligand P(CH2CH2PMe2)3L.D. Field,* B.A. Messerle,* R. Smernik, T.W. Hambley and P. Turner, Dalton Transactions, 1999, 2557-2562.
  5. Rhodium Complexes Containing Bidentate Imidazolyl Ligands: Synthesis and Structure, S. Elgafi, L.D. Field,* B.A. Messerle, T.W. Hambley, and P. Turner, Journal of Organometallic Chemistry, 1999, 588, 69-77.
  6. Structure and Dynamics in Metal Phosphine Complexes using Advanced NMR Studies with Parahydrogen Induced Polarisation, B.A. Messerle, C.J. Sleigh, M.G. Partridge, and S.B. Duckett, Dalton Transactions, 1999, 1429-1435.
  7. Measurement of Magnitude and Sign of Heteronuclear Coupling Constants in Transition Metal Complexes, G. Otting,* L.P. Soler and B.A. Messerle, Journal of Magnetic Resonance, 1999137, 413-429 (Correction/Addition, 1999139, 186).
  8. Synthesis and Properties of Iron(II) Hydride Complexes Containing the Tripodal Tetraphosphine Ligand P(CH2CH2PMe2)3, L.D. Field,* B.A. Messerle,* and R. Smernik, Inorganic Chemistry, 1997, 36, 5984-90.
  9. 1H detected multinuclear NMR Experiments for the Measurement of Small Heteronuclear Coupling Constants in Organometallic Complexes, G. Otting, B.A. Messerle,* and L.P. Soler, Journal of the American Chemical Society, 1997119, 5425-5434.
  10. Iron Complexes Containing the Tripodal Tetraphosphine Ligand P(CH2CH2PMe2)3L.D. Field, B.A. Messerle, R. Smernik, T.W. Hambley and P. Turner, Inorganic Chemistry, 1997, 36, 2884-92.
  11. The Synthesis of Novel Ruthenium Complexes Containing Bidentate Imidazole-Based Ligands, S. Elgafi, L.D. Field,* B.A. Messerle,* T.W. Hambley, and P. Turner, Dalton Transactions, 1997, 2341-2345.
  12. Trisimidazole Complexes of Ruthenium and Osmium, S. Elgafi, B.A. Messerle, L.D. Field,* I. Buys, and T.V. Hambley, Journal of Organometallic Chemistry, 1997538, 119-128.
  13. NMR Studies on Ligand Exchange at IrH2Cl(CO)(PPh3)2 and IrH2Cl(PPh3)3 by Parahydrogen Induced Polarisation, C.J. Sleigh, S.B. Duckett and B.A. Messerle, Chemical Communications, 1996, 2395.
  14. 1H Detected, Gradient-Enhanced 15N and 13C NMR Experiments for the Measurement of Small Heteronuclear Coupling Constants and Isotopic Shifts, G. Otting, B.A. Messerle,* and L.P. Soler, Journal of the American Chemical Society, 1996, 118, 5096-5021.
  15. Activation of C-H bonds in Thiophenes by Rh(PMe3)2(CO)Cl: A Low Temperature NMR Study, M.G. Partridge, L.D. Field,* and B.A. Messerle, Organometallics, 1996, 15, 872-7.
  16. Combined NMR and Molecular Mechanics Study of the Binding of Dichloro(1,4-diazacycloheptane)platinum(II) to the Dinucleotide, d(GpG), T.W. Hambley,* E.C. Ling and B.A. Messerle, Inorganic Chemistry, 1996, 35, 4663-4668.

1991-1995


  1. Rapid Characterization of Rhodium Dihydrides by NMR Spectroscopy Using Inverse 2-Dimensional Methods and Parahydrogen, S.B. Duckett, G.K. Barlow, M.G. Partridge, and B.A. Messerle, Dalton Transactions, 1995, 3427-3429.
  2. The Signs of Heteronuclear Coupling Constants in Octahedral Rhodium Complexes Determined using High Resolution 2D NMR, M.G. Partridge, B.A. Messerle, and L.D. Field, Organometallics, 1995, 14, 3527-3530.
  3. Formation of a Novel Dipyrrolopyrrole Mediated by Diazabutadiene Complexes of Iron, I. Buys, S. Elgafi, L.D. Field, T.V. Hambley, and B.A. Messerle, Inorganic Chemistry, 1994, 33, 1539-42.
  4. The.Synthesis of New Tetradentate Oligophosphine Ligands, N. Bampos, L.D. Field, B.A. Messerle, and R.J. Smernik, Inorganic Chemistry, 1993, 32, 4084-4088.
  5. Measurement of Heteronuclear Coupling Constants in Organometallic Complexes using High-resolution 2D NMR, N. Bampos, L.D.Field, and B.A.Messerle, Organometallics, 1993, 12, 2529-2535.
  6. The Structure of Dilithiated (E)-1,4-bis(trimethylsilyl)but-2-ene by X-ray crystallography and 7Li HOESY, L.D. Field, M.G. Gardiner, B.A. Messerle, and C.L. Raston, Organometallics, 1992, 11, 3566-3570.
  7. Comparison of the Solution Structure Conformations of Human[Zn7]-Metallothiein-2 and [Cd7]-Metallothionein-2 Using Nuclear Magnetic Resonance Spectroscopy, B.A. Messerle, A. Schäffer, M. Vasák, J.H.R. Kägi, and K. Wüthrich,  Journal of Molecular Biology, 1992, 225, 433-443.
  8. Methane Activation by Fe(DMPE)2H2 in Liquid Xenon Solution, L.D. Field, A.V. George, and B.A. Messerle, J. Chem. Soc. Chem. Commun., 1991, 1339-41 Reviewed by R.L.Burwell Jr. in CHEMTRACTS, 1991, 3, 352-355.
  9. Metallothionein-2[113Cd7] (Human)” in “Macromolecular Structures 1990, B.A. Messerle, A. Schäffer, M. Vasák, J.H.R. Kägi, and K. Wüthrich, eds. W. Hendrickson and K. Wüthrich, Current Biology Ltd, 1991.
  10. Methane Activation by Fe(DMPE)2H2 in Liquid Xenon Solution, L.D. Field, A.V. George and B.A. Messerle, J. Chem. Soc. Chem. Commun., 1991, 1339-1341.
  11. Synthesis, Reactivity and NMR Studies of Dilithiated (E)-1,4-bis(trimethylsilyl)but-2-ene and (E)-1,4-bis(trimethylsilyl)-2,3-dimethylbut-2-ene, L.D. Field, M.G. Gardiner, C.H.L. Kennard, B.A. Messerle, and C.L. Raston, Organometallics, 1991, 10, 3167-3172.
  12. A Sample Tube for Medium Pressure NMR Spectroscopy – NMR Spectroscopy in Liquid Xenon Solution, L.D. Field, A.V. George, B.A. Messerle and H. Ionn, Anal. Chem., 1991, 63, 184-186.
  13. Kinetics of Rearrangement of H2FeP(CH2CH2CH2P(CH3)2)3 by inversion-transfer-recovery NMR, L.D. Field, N. Bampos and B.A. Messerle, Magnetic Resonance Chemistry, 1991, 29, 36-39

1986-1990


  1. Amide Proton Exchange in Human Metallothionein-2 measured by Nuclear Magnetic Resonance Spectroscopy, B.A. Messerle, M. Bos, A. Schäffer, M. Vasák, J.H.R. Kägi, and K. Wüthrich, Journal of Molecular Biology, 1990, 214, 781-786.
  2. The three-dimensional Structure of Human [Cd7]-Metallothionein-2 in Solution determined by Nuclear Magnetic Resonance Spectroscopy, B.A. Messerle, A. Schäffer, M. Vasák, J.H.R. Kägi and K. Wüthrich, Journal of Molecular Biology, 1990, 214, 765-779.
  3. Solvent Suppression using a Spin Lock in 2D and 3D NMR Spectroscopy with H2O Solutions, B.A. Messerle, G. Wider, G. Otting, C. Weber, and K. Wüthrich, Journal of Magnetic Resonance, 1989,85, 608-613.“This paper was selected as paper 33 in “NMR In Structural Biology, A collection of papers by K. Wüthrich”, World Scientific, 1995
  4. Stereospecific Assignment of the Methyl 1H NMR Lines of Valine and Leucine in Polypeptides by Non-random 13C Labelling, H. Senn, B. Werner, B.A. Messerle, C. Weber, R. Traber, and K Wüthrich, FEBS Lett., 1989,249, 113-118.
  5. Site Selective Observation of Nuclear Overhauser Effects in Proteins via Isotopic labelling, M. Rance, P.E. Wright, B.A. Messerle, and L.D. Field, Journal of the American Chemical Society, 1987,109, 1591-1593.
  6. The Correlation of 1H and 13C NMR Spectra by selective Inverse INEPT. Assignment of the proton and carbon spectra of Methyl (5R*,6S*,8Z,11Z,14Z)-5,6-epoxyeicosa-8,11,14-trienoate, M.J. Crossley, L.D. Field, J.G. Gosper, and B.A. Messerle, Magnetic Resonance Chemistry, 1987,25, 297.
  7. Relayed Coherence Transfer from a Heteronuclear through an Extended Proton Spin System, L.D. Field and B.A. Messerle, Journal of Magnetic Resonance, 1986, 66, 483-490.

1985


  1. X ® H ® H Heteronuclear Relayed Coherence Transfer. The Selective Observation of Protons in Spin Systems containing Heteronuclei, L.D. Field and B.A. Messerle, Journal of Magnetic Resonance, 1985, 62, 453-460.
  2. NMR Studies of the Structure and Dynamics of Monomeric Hemoglobins and Myoglobins in: Magnetic Resonance in Biology and Medicine, P.E. Wright, K.J. Cross, B.C. Mabbutt, B.A. Messerle, and J.E. Wellington, editors G. Govil, C.L. Khetrapal, and A. Saran, Tata McGraw-Hill, New Delhi, 1985,pp131-151.

Our people

Current members

Dr Roy McBurney ORCID ResearcherID

Roy was awarded a PhD from the University of Edinburgh (UK) in 2009 where he also completed his Masters in Chemistry. Roy’s PhD focused on using transition metal ions to direct the formation of intricate molecular topologies and molecular shuttles in group of Prof. David Leigh. After a brief post-doc at Durham University (UK), Roy joined Prof. John Walton at the University of St Andrews (UK) to develop titania as a heterogenous catalyst and explore organic radical reactions. Roy’s last job before leaving the UK was at the University of Strathclyde were he had the enviable job of spending 12.4M GBP (~23M AUD) on processing and analysis instruments for pharmaceutical research at the Centre for Continuous Manufacture and Crystallisation (CMAC) under Prof. Alastair Florence. Roy’s exploring all that Australia and New Zealand can offer, including the spiders and snakes!

Mark Gatus

Dr Mark Gatus ORCID

Mark Gatus attained his BSc at UNSW in 2010 completing his final honours year research project in the Messerle group working on cooperative bimetallic catalysis. His interest in bimetallic catalyst design has continued into his PhD where he holds the group records for longest ligand synthesis and most complicated NMR assignment. He is also kept very busy raising his mischievous 1 year old son Jack who is quickly learning chemistry terminology and is expected to graduate with a Masters in advanced catalysis at the tender age of 2, possibly several months before his father.

Dr Indrek Pernik

Indrek was awarded a DPhil from the University of Oxford in 2014 in the group of Prof. Andrew Weller. His project was concentrated on synthesising novel small bite angle rhodium catalysts for intermolecular hydroacylation reaction. Prior to this, Indrek gained a Master’s degree at the University of Bristol, with a year at the University of North Carolina at Chapel Hill. During the studies he had opportunities to carry out projects under the supervision of Prof. Maurice Brookhart and Prof. Paul Pringle, followed by a year working at an industry. Before taking up the position at the Messerle group, Indrek worked as a Post-Doctoral Research Fellow at Monash University at the group of Prof. Cameron Jones to get away from transition metals for a bit and gain some understanding of the main group chemistry. At the Messerle group Indrek is back to working on transition metal chemistry, in particular his project concentrates on bimetallic complexes and their deposition on surfaces. Outside the lab Indrek is trying to do his best to explore Australia and keep sporty, although the latter still needs a bit of work…

RalphRalph Lam ORCID

Ralph was awarded a BSc at UNSW after completing an Honours project in the Messerle group in 2014 and then started his Year 2 MRes at Macquarie Uni in 2015 with Prof. Messerle. Ralph began his PhD in 2016, initially investigating the catalytic and electrochemical properties of a range of metal complexes. Ralph has shifted his research focus to using CO2 as a building block in organic synthesis with the aid of transition metal catalysts. Outside the lab, Ralph spends most of his time training in the bush, and has (finally) decided to learn surfing.

Matt Peterson ORCID

Matt completed a BEng / BSc combined degree (Industrial Chemistry/Chem) at UNSW in 2012. During undergraduate studies he worked at a variety of companies within the University’s coveted Co-op Program (namely BlueScope Steel and Siemens Water Technologies). Since graduating he spent 12 months at the Australian Nuclear Science and Technology Organisation (ANSTO) in their Graduate Program, working on enabling new diagnostic radiotracers to reach the clinical environment. In 2014 he returned to the Messerle Group to complete his PhD, focusing on bimetallic catalysts, using both homogeneous and surface immobilised systems to catalyse tandem reactions. Outside chemistry, Matt’s current obsessions are coffee (coffee coffee!) and German Shepherds (despite his inner city apartment not allowing him to own one, yet).

Masahiro Kouno 

Masahiro is visiting the Messerle group for a 3 month placement. He is doing his PhD at Osaka University under the supervision of Prof. Takumi Konno.

Danfeng Wang

Danfeng is a proactive person full of passion for chemistry. Before joining Messerle’s group she worked at WuXi AppTec Co. Ltd, China, as a researcher. However, her passion for chemistry and an eagerness to learn cutting-edge chemistry became the driving force to become a PhD student. Danfeng joined the Messerle Group with the aid of a stipend from the Chinese Scholarship Council. Now with the organometallic chemistry she is learning, she aims to synthesise high-performance hybrid organometallic photo-catalysts aiming to lower energy consumption and environmental pollution, creating environmental-friendly and sustainable catalysts. Her hobbies are traveling, swimming and playing ping-pong, she also likes colourful things and imagining all the chemistry behind the colours!

Josh Tompsett

Josh is in the 2nd Year of the MRes program at Macquarie University and is investigating tandem catalysis with bimetallic complexes. He loves football.

Previous members

Member Life after the Messerle group
Dr Samantha Binding 2017 (Post-doc)
Ashwin Gopalan Nair 2017 (PhD)  Badminton instructor
Andrew Wheals 2016 (MRes)  Network Engineer
Chin Min Wong 2016 (PhD)
Sandra Choy 2016 (PhD) Policy Graduate Program, Department of Industry, Innovation and Science
Barney Walker 2015 (Post-doc) Partner in a Sustainability and Clean Technology Consultancy and Executive Search Firm
Michael Page 2014 (Post-doc)
Andrey Tregubov 2013 (PhD) Post-doc, University of Illinois, USA; Senior Research Fellow, Moscow Institute of Physics and Technology
Yeng Ying Lee 2013 (MSc) Information Analyst, Johnson Matthey, UK
Giulia Mancano 2013 (PhD) Post-doc, University of Reading, UK
Marina Timerbulatova 2013 (PhD) Management Trainee, ANZ
Matthew Peterson 2012 (Hons) Graduate program, ANSTO, Sydney
Oanh Nguyen 2012 (PhD)
Carol Hua 2011 (Hons) PhD, University of Sydney
Joanne Ho 2010 (PhD) Research scientist, Kemin Industries, Singapore
Bradley Man 2010 (PhD) Patent examiner, IP Australia, Canberra
Laurent Poorters 2009 (Post-doc)
Rebecca Wilson 2008 (Post-doc)
Serin Dabb 2008 (PhD) Managing editor, Royal Society of Chemistry, Cambridge UK
Michael Page 2008 (PhD) Post-doc, University of Bath, UK
Richard Hodgson 2007 (Post-doc)
Danielle Kennedy 2007 (PhD) Research scientist, CSIRO, Melbourne
Adele Shasha 2007 (PhD) Assistant Manager, UNSW analytical centre
Katherine Sage 2007 (Hons)
Zheng Li 2007 (Hons)
Khuong Vuong 2006 (PhD) Post-doc, Nottingham University, UK
Sarah Rumble 2006 (PhD) Manager (new chemical assessment), NICNAS, Sydney
Sophie Beeren 2005 (Hons) PhD, Cambridge University, UK
Martin Drinkwater 2005 (Hons)
Emily Waller 2005 (Hons) Scientist, National Deuteration Facility, ANSTO, Sydney
German Ferrando 2005 (Post-doc)
Connie Diakos 2002 (PhD)
Suzanne Burling 2002 (PhD) Senior scientist, ANSTO, Sydney
Vivienne Munk 2001 (PhD)
Melanie Young 2001 (Hons)
Vickie-Anne Tolhurst 2000 (Hons)
Linnea Soler 1999 (PhD) Lecturer, University of Glasgow, UK

International practicum students

The Messerle group has been fortunate to host a number of international practicum students over the years. The mutual exchange of knowledge and experience has been greatly rewarding for both us and our guests and it is a great opportunity to develop relationships with researchers from across the globe.

Here are some of our recent guests:

GuestInstitution
Tobias Setzer2011Ruprecht Karl University of Heidelberg, Germany
Jan Schumaker2011Ruprecht Karl University of Heidelberg, Germany
Nathalie van der Molen2010Hanze University, Netherlands
Astrid Knudtsen2009University of Aarhus, Denmark
Kim Lebek2007University of Aarhus, Denmark
Tina Mittag2004University of Aarhus, Denmark
Ciara Chiardi2002University of Florence, Italy
Manuela Rehr2000University of Marburg, Germany

Engage with us

Collaborations

We have several longstanding and fruitful collaborations with research groups both across the globe and within Australia. As such, graduate students in the Messerle group frequently get the opportunity to travel in order to work directly with our collaborators and further develop their promising scientific discoveries.

Computational Inorganic Chemistry


Computational Inorganic Chemistry with Prof. Stuart Macgregor, Heriot Watt University, Edinburgh, UK and Prof. Odile Esienstein, University Montpellier 2, France.With Prof. Stuart Macgregor, Heriot Watt University, Edinburgh, UK and Prof. Odile Esienstein, University Montpellier 2, France.

Understanding the mechanism of any transition metal catalysed reaction pathway is a critical part of the design process when developing of new more efficient catalysts. To do this we use computational chemistry to determine likely reaction pathways and we work closely with the Macgregor and Eisenstein groups to further understand these processes

Prof. Macgregor has over 20 years of experience in this field and has authored over 50 papers and several book chapters on the subject of the mechanism of TM-catalysed reactions.

A link to the Macgregor Lab can be found here.

Prof Esienstein is Head of the group of theoretical chemistry of the Institut Gerhardt in the University Montpellier 2, France and has over 245 publications on the subject of theoretical modelling of transition metal catalysis.

A link to the Eisenstein group website can be found here.

Robust linking of organometallic complexes onto inert carbon supports.


Robust linking of organometallic complexes onto inert carbon supports with Prof. J. Gooding, UNSW, Australia.With Prof. J. Gooding, UNSW, Australia.

We have recently begun to develop heterogeneous catalysts based on Rh and Ir complexes covalently bound to various forms of inert carbon. We are exploring these new frameworks in collaboration with the Gooding Group who have extensive experience in the modification and characterisation of surfaces for the development of biointerfaces, biosensors and molecular electronics. Together with the Gooding group we use X-ray photo electron spectroscopy, Raman spectroscopy, and thermogravimetric analysis as well as electrochemistry to investigate the composition of our functionalised carbonaceous materials and gain insight into their performance as heterogeneous catalysts.

Professor Justin Gooding is a Director of the Australian Centre for NanoMedicine and is based at the School of Chemistry at The University of New South Wales. He is a world renowned surface chemist and electrochemist with extensive experience in the modification of surfaces with self-assembled monolayers for the development of biointerfaces, biosensors and molecular electronics.

A link to the Gooding group website can be found here.

Solid State NMR using para hydrogen


Solid State NMR using para hydrogen with Prof. S. B. Duckett, The University of York, UK.With Prof. S. B. Duckett, The University of York, UK.

We have a current collaboration with the Duckett Lab that focuses on the development of new techniques for understanding the molecular structure of catalysts in soluction and on surfaces using parahydrogen. Prof. S. B. Duckett is internationally known for his contributions to the application of parahydrogen NMR to understanding the structures and mechanisms of organometallic catalysts. Prof Duckett is the Director of the York Centre for Magnetic Resonance, one of the largest NMR Facilities in the UK.

A link to the Ducket Lab can be found here.

Boron and silicon based pincer ligands for environmentally responsible catalysis


Boron and silicon based pincer ligands for environmentally responsible catalysis with Prof. Tony Hill, ANU, Canberra, Australia.With Prof. Tony Hill, ANU, Canberra, Australia.

The production of everyday chemicals (pharmaceuticals, agrochemicals, polymers) comes at an economic and environmental price. Using transition metal catalysts can significantly reduce the environmental impact of both the associated energy requirements and waste products. In collaboration with the Hill group we seek to develop new classes of catalysts containing ligands based on the unconventional elements boron and silicon.

Prof. Anthony F. Hill specializes in synthetic organometallic and coordination chemistry. Prof. Hill’s research investigates the nature of metal carbon bonding and endeavours to develop an understanding of the interaction of carbon with transition and main group metals.

A link to the Hill group can be found here.

Transition metal catalysis


Transition metal catalysis with Prof. Les Field, UNSW, Sydney, Australia.With Prof. Les Field, UNSW, Sydney, Australia.

We have a longstanding collaboration with the Field group utilising catalytically active organometallic species for the synthesis of high value heterocyclic compounds. Prof. Field’s main areas of research are organometallic chemistry, nitrogen fixation, catalysis and NMR spectroscopy. He is the author of more than 170 scientific papers, 4 textbooks and a number of book chapters.

A link to the Field group can be found here.

News and events

2017

January

  • 2016 was a busy year with 3 PhD completions!
  • Photos from the day Ashwin received the good news!

2016


August

  • Ashwin’s work on “Ruthenium Complexes of Hemilabile Pincer Ligands: Synthesis and Catalysing the Transfer Hydrogenation of Ketones” gets published! Dalton Trans. 2016, 45, 14335-14342.
  • Shelly has headed off to University of New Brunswick to do an organic synthesis project.
  • Josh joins us in the lab for four weeks as our latest MRes Year 1 student.

July

  • Mark, Ralph, Sam and Barbara head down to Melbourne for ICOMC 2016.
  • The group all head over to UNSW for the 29th Reactive Organometallics Symposium where Mark and Sam are giving talks. The chemistry-themed cookies are perfect to cheer up Sam and Roy after watching the Brexit counter tot up.
Sandy and Barbara at UNSW for graduation

April

  • Congratulations to Shelly, who won the award for Best Student in her cohort at the Faculty of Science and Engineering’s Awards Evening this month!

January

  • The new year gets off to a great start: Sandy received fantastic results for her PhD thesis!
  • Chin heads to the UK for collaborative NMR work with Prof. Simon Duckett at the University of York.
  • New Postdoctoral Researcher Dr Roy McBurney joins us from Scotland.
  • A busy month! New starters Adam and Neil join us for 6-week Summer projects, Andrew returns to start his MRes Year 2, Ralph is back to commence his PhD project, and Sandy returns as a Postdoctoral Researcher.

2015


December

  • 8-11th December: We all head to USyd for OZOM9. Chin, Ashwin, and Sam give talks and Mark presents a poster.
  • Chin’s latest paper “A versatile method for the preparation of carbon-rhodium hybrid catalysts on graphene and carbon black” is accepted into Chemical Science: Chem. Sci., 2016, Advance Article
  • 15-20th December: Barbara heads to Pacifichem in Hawaii to present Mark and Sandy’s PhD work
  • Ralph can now call himself a Master of Research!

November

  • 6th November: We host our first event at Macquarie University: the 28th Reactive Organometallics Symposium (ROMS 28), at the Hearing Hub.

October

  • Macquarie MRes Year1 project students Alex and Andrew join us for 4 weeks each.

September

 Stopping for coffee at the Big Sheep in Goulburn, en route to ROMS 27

Ralph and Vera both have papers accepted in Organometallics!

June

  • Dr Samantha Binding joins us from the UK as our new Post-doctoral Researcher.
  • Shelly Wang joins us as we head to Canberra for ROMS 27 at ANU, a steep start to her Merit Scholarship!

May

  • Dr Barney Walker leaves for a new job in New Zealand. We wish him the best of luck.

January – May

  • Our brand new lab at Macquarie University takes shape!

2014


July

  • 13-18th July – 26th ICOmC- Sapporo
26th International Conference on Organometallic Chemistry - Sapporo, Japan26th International Conference on Organometallic Chemistry - Sapporo, Japan26th International Conference on Organometallic Chemistry - Sapporo, Japan26th International Conference on Organometallic Chemistry - Sapporo, Japan26th International Conference on Organometallic Chemistry - Sapporo, Japan
  • 21-25 July – 41st ICCC- Singapore
  • 22-25 July- 8th OZOM- Magnetic Island (Brisbane)

Congrats on a Poster Prize Matt!!

March

  • Ralph Lam commences his Honours year with us.
  • Matt Peterson & Vera Diachenko return to us to begin their PhDs
  • Artur Kochanke joins us for a 6 month exchange from Georg- August University, Goettingen

2013


December

November

  • 8th November: We hold the 24th Reactive OrganoMetallics Symposium (UNSW) and welcome the annual visit of our Canberran cousins! (Tony Hill group)
  • Andrey’s paper entitled “Rh(I) complexes bearing N,N and N,P ligands anchored on glassy carbon electrodes towards recyclable hydroamination catalysts” is published in JACS: J. Am. Chem. Soc, 2013, 135, 16429-16437. Good Job!

October

  • 31st October- 13th November: Research labs shut down at the School of Chemistry as new flooring is installed, giving us time to catch up on all our ‘house’ work and writing! It’s a little sad and so very strange to see our work spaces empty and chemicals imprisoned though!
  • 27th-31st October 2013: Prof. Messerle is invited to present at the ANZMAG- 5th Asia Pacific NMR Symposium (ANZMAG-APNMR, Brisbane) as a Plenary lecturer.
  • We celebrate our 100th paper withAndrey presents “Rh(I) complexes bearing N,N and N,P ligands anchored on glassy carbon electrodes towards recyclable hydroamination catalysts” in J.Am.Chem.Soc (published online on 2nd October 2013)

September

  • Dr. Barney Walker joins us as our new Post-Doctoral Researcher!
  • “Directing the regioselectivity of Rhodium(I) catalysed cyclisation of 2-alkynyl benzoic acids” in Polyhedron. (published on 18th September 2013).
    Marina, Mark and Khuong publish their findings on “Bimetallic complexes for enhancing catalyst efficiency – Probing the relationship between activity and intermetallic distance” in Organometallics (Published online on 6th September 2013) as a collaborated product with Prof. Stuart Macgregor
    August:
  • Sandra Choy returns from a 2 month education with the Stuart Macgregor Group (Heriot-Watt University, Scotland)
Sandra ChoyStuart Macgregor Group
  • Khuong publishes one of the last projects he was working on with us as a report on “Cationic Rh and Ir complexes containing bidentate imidazolylidene-1,2,3-triazole donor Ligands: synthesis and preliminary catalytic studies” published in Dalton Transactions (published online on 20th August 2013)
  • Sandra’s long -long awaited findings on “Cooperative Catalysis : Large Rate Enhancements with Bimetallic Rhodium Complexes” published in Organometallics (published online on 16th August 2013) is finally out after 3 years of anticipation.

July

  • 25-26th July 2013: Sandra scoops another poster prize at the 47th Universities of Scotland Inorganic Chemistry conference (USIC, Edinburgh)
    • Poster titled “Flat Rh(I) Complexes for Catalysed C-X Bond Formation – Enhanced Cooperativity”
  • 30th June – 4th July 2013: Barbara, Michael, Mark and Sandra attends the 20th EuCheMS Conference on Organometallic Chemistry on the other side of the world at the University of St Andrews in Scotland.
    • Sandra wins a Poster Prize for her poster titled “Flat Rh(I) Complexes for Catalysed C-X Bond Formation – Enhanced Cooperativity”

The Macgregor, Messerle and Weller groups "band" together on the 'set' of Chariots of Fire

May

Congratulations to all 2012 prize winners.

  • The CETEC Prize for Best Performance in Honours Thesis- Chin Min Wong
  • The Angyal Prize for Best Performance in Honours Chemistry – Chin Min Wong
  • The UNSW Chemical Society George Wright Prize for Meritorius performance in Level 2 Chemistry Courses – Sharon Yu
  • The RACI Analytical Chemistry Group Prize for Best performance in Level 3 Analytical Chemistry – Vera Diachenko
  • The Du Pont Prize for Best Performance in B.Sc. 3 year degree in Chemistry, Overall “top” of Chemistry – Kiara Olrich
  • The School of Chemistry Prize and School Medal for best performance in Level 3 Chemistry – Kiara Olrich
  • The UNSW Chemical Society Dwyer Prize for Best performance in Level 3 Inorganic Chemistry – Kiara Olrich
  • The Inglis Hudson and Jeffrey Bequests for Best performance in Level 3 Organic Chemistry- Kiara Olrich
  • The Bosworth Prize and Medal for Best performance in Level 3 Physical Chemistry- Kiara Olrich
  • UNSW Postgraduate Research Student Support Award for Conference Travel – Mark Gatus & Sandra Choy
  • Postgraduate Teaching Fellowships – Mark Gatus & Sandra Choy

March

  • Ashwin Nair joins us from the University of Waikato (N.Z) to take on a PhD candidature.

January

  • 7th Australasian Organometallics Discussion Group Meeting (OZOM7)
  • Farewell to Dr. Khuong Vuong as he leaves for a new position in Singapore
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