Biomolecular Discovery and Design Research Centre

Biomolecular Discovery and Design Research Centre

Biomolecular Discovery and Design Research Centre

DEVELOPING, IMPROVING AND APPLYING BIOMOLECULAR ANALYSIS TO LIVING SYSTEMS TO HELP CURE DISEASE, PRODUCE BETTER FOOD AND ADAPT TO ENVIRONMENTAL CHANGE.

Our research aims to increase the understanding of the molecular diversity and networks driving living organisms: to discover new ways to cure disease, produce better food and adapt to environmental change. Studying biomolecular sciences helps us to understand the function of the many molecular systems that operate in the cell, as part of our quest to unravel the complexity of biology.

We have consolidated our research streams into a systems biology approach, which recognises that an organism must be viewed as an integrated network of genes, proteins, protein modifications, metabolites and biochemical reactions. Also, with the emergence of synthetic biology we are not bound anymore by the ‘natural’ molecular components of life but can build them according to our own specifications.

The Biomolecular Discovery and Design Research Centre has evolved from the BioMolecular Frontiers Research Centre (BMFRC, 2008-2016) in order to expand its research into synthetic biology whilst continuing the critical research collaborations that have been developed in biomolecular technology and ‘Omics (genomics, proteomics, glycomics, transcriptomics), including a new emphasis on metabolomics.

The centre is embedded within the Department of Chemistry and Biomolecular Sciences, Faculty of Science, at Macquarie University. We interact closely with the Australian Proteome Analysis Facility (APAF), which offers state-of-the-art research infrastructure and services.

Our research

The Biomolecular Discovery and Design Research Centre (BDDRC) aims to bring together diverse innovative approaches to the study of biological problems, using biomolecular analytical technologies.

Our research uses Genomics, Proteomics, Glycomics and Metabolomics approaches to serve a wide variety of specific research areas depicted below. These are underpinned by strong Bioinformatics capabilities. The outcomes flow into applications in Science, Agriculture, Nano Technology and Medical Discovery.

Our research aims to increase the understanding of the wide-ranging physiology displayed by living organisms as a result of their underlying genetic diversity.

Today's ‘omics tools of genomics, proteomics, glycomics and bioinformatics are allowing the rapid discovery and analysis of gene inventories and phenotypes across a range of life-science applications including building new organisms through synthetic biology. These are key approaches of many groups now concentrated in the Centre and this integration is enabling new insights into a wide range of biological systems.

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