Auditory hyperacusis in Williams syndrome
At present, we have very little idea of the underlying causes of hyperacusis. Previous research on Williams syndrome has ruled out problems with the workings of the ear itself, so we think that the cause is more likely to be in how the brains of people with Williams syndrome process sounds. In this study we are using magnetoencephalography (MEG) to measure the brain responses of young people with Williams syndrome to sounds. We're interested in how large the responses are, how the brain activity synchronizes to rapid modulations in the intensity of the sounds, and how they react to unexpected changes in the pitch of the sound.