Scholarships for domestic candidates

Scholarships for domestic candidates

Click on the faculty, then scholarship titles below to reveal more information about the specific projects or scholarship opportunities.

General Scholarships

Macquarie University Indigenous Research Pathway

Name of Scholarship Eligible Program Status/Reference Closing Date
Macquarie University Indigenous Research Pathway Program
MRES
MPHIL
PHD
OPEN (All Year)

The Macquarie University Indigenous Research Pathway Program provides scholarship support to Indigenous Australians to enrol in a postgraduate degree including Master of Research, Master of Philosophy, or Doctor of Philosophy, in any field of research.

The aim of the Program is to encourage and increase the number of Indigenous Australians undertaking postgraduate research study with a view to increasing the number of Indigenous Australian academic staff. The Program provides recipients with the opportunity to access:

  • Mentoring from academic and professional staff and fellow postgraduate students
  • Advanced research preparation and skills development
  • Career development and opportunity
  • The opportunity to present your research work at local, regional and national conferences

Candidates who are successful in receiving an Indigenous Research Pathway Program scholarship are welcomed into the host Faculty and encouraged to participate fully in academic life. As well as scholarship funding, there may be opportunity to undertake further paid employment such as tutoring, marking or Faculty activities.

Value and Tenure: The value and tenure of the scholarship varies according to the degree being undertaken, as follows:

  • Master of Research (MRes)
    For candidates enrolling in an MRes, the scholarship stipend is valued at $26,682 per annum (tax exempt) for up to 2 years.
  • Master of Philosophy (MPhil)
    For candidates enrolling in an MPhil, the scholarship stipend is valued at $36,682 per annum (2017 rate), tax exempt and indexed annually, for up to 2 years. (This funding consists of the standard scholarship stipend based on the Commonwealth Government scholarship minimum funding rate, plus an additional $10,000 pa fixed rate supplementary stipend.)
  • Doctor of Philosophy (PhD)
    For candidates enrolling in a PhD, the scholarship stipend is valued at $36,682 per annum (2017 rate), tax exempt and indexed annually, for up to 3 years. (This funding consists of the standard scholarship stipend based on the Commonwealth Government minimum scholarship funding rate, plus an additional $10,000 pa fixed rate supplementary stipend.)

For PhD and MPhil candidates, leave and other conditions are generally equivalent to that of the Commonwealth Government Research Training Program (RTP) scholarship and Macquarie University Conditions of Award. If the candidate has previously enrolled in study towards a research degree, the duration of the scholarship will be reduced by this period of prior enrolment. This is known as advanced standing.

Eligibility: To be eligible, candidates must:

  • Be enrolled or enrolling in a Master of Research (either year 1 or year 2), or a Master of Philosophy (MPhil), or a Doctor of Philosophy (PhD).
  • Meet the University's minimum scholarship rating criteria.
  • Be an Indigenous Australian

Application: Applicants should refer carefully to candidature admission and scholarship criteria before lodging an application. All applicants will need to attach Letter of Confirmation of Aboriginality OR a completed Statutory Declaration (see below). All applicants will need to arrange for two academic referee reports to be submitted to the Higher Degree Research Office (HDRO). Academic referee reports are available at the Forms page.

For MRes applications:

For MPhil/PhD applications:

  • Information for MPhil and PhD applicants can be found at Research Degrees.
  • Applicants should also refer to the University's scholarship requirements. Successful applicants will usually have a solid academic record, a history of scholarships/prizes at the undergraduate level; and may have undertaken peer-reviewed research activity. Further information can be found at HDR Scholarship Requirements.
  • Applicants applying for MPhil or PhD, or for an MRes/PhD Bundle*, should apply using the HDR Candidature and Scholarship Application form.

*An MRes/PhD Bundle is for entry into year 2 of the MRes program, followed by PhD.  Progression to the PhD is conditional up successful completion of the MRes Year 2 program.

Applicants for admission to PhD, who are (counter) offered entry to MRes Year 2 with a provisional 3-year PhD and who rank competitively for scholarship, may be offered a scholarship for MRes Year 2. Candidates must rank competitively for scholarship for continuation of the scholarship into the PhD candidature.

NOTE: The Conditions of Award of this scholarship are the same as the RTP and MQRTP Conditions of Award.

Statutory Declaration: The Indigenous Research Pathways Program is open to Indigenous Australians only. Applicants must supply either a copy of their Letter of Confirmation of Aboriginality or a completed Statutory Declaration to confirm their Indigeneity (available below).

Contact: For application queries, contact the HDRO Scholarships Officers at hdrschol@mq.edu.au. For other queries, contact the Head of Department, Department of Indigenous Studies – Walanga Muru - Office of Indigenous Strategy (OIS).

Please quote the scholarship reference 'Indigenous Research Pathway Scholarship' on your application.

Faculty of Arts

Ancient History - Forging Antiquity: Authenticity, forgery and fake papyri

Faculty of Arts: Ancient History – Forging Antiquity: Authenticity, forgery and fake papyri
MRES/PHD 2017456         31 DECEMBER 2017

Geography and Planning - Housing & Community Development (Macquarie Park)

Faculty of Arts: Geography and Planning - Housing & Community Development (Macquarie Park)
PHD 2016315 15 APRIL 2017

Department

Geography and Planning

Project Name

Housing & Community Development (Macquarie Park)

Project Description

The project will investigate urban planning, housing and community development in the Macquarie University Station Precinct with a view to providing strong foundations for strategic understanding of urban form, structure and function in the area for key stakeholders in local government, community and the university. Applicants should be qualified in urban planning, urban geography or a closely related field with a strong record in community-based research.

The successful candidate MUST be enrolled at Macquarie University no later than 30 June 2017.

If you are applying for this PhD and scholarship allocation, please notify hdrschol@mq.edu.au as soon as you submit your application.

Other Important Information

The project is co-funded by City of Ryde Council as part of the Macquarie-Ryde Futures Project.

This scholarship is available to eligible candidates to undertake: 

  • Direct entry into a 3 year PhD program.  

The value and tenure of the scholarship is: 

  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)) 
  • For international candidates, the scholarship includes Macquarie University tuition fees for up to three years  

Applicants will need to Apply for a research degree and scholarship at Macquarie University and arrange for two academic referee reports to be submitted to the Higher Degree Research Office.  


The form can be downloaded from the Forms page.    

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines.  
 
Refer to the Rating Scholarship Applicants section for more information about these guidelines. 

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer. Please quote the scholarship code on your application. 

MUST be enrolled at Macquarie University no later than 30 June 2017 

Contact Name: Associate Professor Kristian Ruming

Contact Email: kristian.ruming@mq.edu.au

Contact Phone: +61 2 9850 8393

Philosophy/Macquarie Law School - A Relational Theory of Procedural Justice

Faculty of Arts: Philosophy/Macquarie Law School – A Relational Theory of Procedural Justice
PHD 2017483         15 June 2017

Department

Philosophy/Macquarie Law School

Project Name

A Relational Theory of Procedural Justice

Project Description

We are seeking a PhD candidate to join an interdisciplinary research project in law and philosophy at Macquarie University.  

The project is concerned with procedural justice in the context of resolving legal disputes. Its overall aim is to develop a theory of procedural justice that builds on relational theory in philosophy by incorporating relational concerns in the moral evaluation of legal procedures.  The project re-evaluates the received theories of instrumentalism and dignitarianism and draws on empirical evidence from social psychology about the public’s perceptions of procedural justice in explaining why the quality of people’s relationships with legal authorities matter. 

The theory will be used to evaluate the procedural practices of a designated legal institution (the New South Wales Civil and Administrative Tribunal).  A case study will investigate the extent to which the theory explains, justifies or provides reasons for revising the procedural practices of the NCAT.

The PhD candidate will either work on the normative aspect or the institutional legal aspects of the project, depending on their qualifications and background.   The candidate will be supported by the strong research environments of the Macquarie University Centre for Agency Values and Ethics, the Philosophy Department and Macquarie Law School. 

This scholarship is available to eligible candidates to undertake either a direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.   

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number on your application.

Contact Name: Professor Denise Meyerson

Contact Email: Denise.Meyerson@mq.edu.au

Contact Phone: +61 2 9850 7079

Faculty of Business and Economics

Faculty of Human Sciences

Faculty of Medicine and Health Sciences

Australian Institute of Health Innovation - Genomics Implementation 2: Consumer perspectives and experiences of the implementation of genomic sequencing in Australian healthcare organisations

Faculty of Medicine and Health Sciences:Australian Institute of Health Innovation - Genomics Implementation 2: Consumer perspectives and experiences of the implementation of genomic sequencing in Australian healthcare organisations
MRES2
PHD
2017158                 28 APRIL 2017

Department

Australian Institute of Health Innovation (AIHI)

Project Name

Genomics Implementation Implementation 2: Consumer perspectives and experiences of the implementation of genomic sequencing in Australian healthcare organisations

Project Description

MRes/PhD position summary:

The Australian Institute of Health Innovation (AIHI) is part of the largest grant on genomics ever awarded by the National Health and Medical Research Council (NHMRC). The Australian Genomics Healthcare Alliance (AGHA) project aims to prepare Australia for the genomics revolution in health care, and will run for five years (2016-2021).

In this project, the PhD student will undertake research with the general public and recipients of genomic sequencing in the existing flagships to identify perceptions and experiences of the implementation of genomic sequencing in healthcare organisations. Investigations will be undertaken primarily using interviews and focus on areas including: (a) perceived public and individual need; (b) perceived and actual benefits; (c) experiences of the process (this will include a comparison to reports of the process from the clinician and service provision perspective); (d) perceived and actual barriers and facilitators to access; (e) perceptions of and plans to disseminate genetic disorder diagnosis information to family members; (f) perceptions of how and plans to manage conditions following diagnosis. New knowledge gained from this PhD will 1) inform the design of information materials for the public and patients about genetic sequencing; 2) help to streamline processes within and between healthcare systems (e.g., GP to hospital); 3) inform the design of interventions to support decision making about sequencing and dissemination of information to family members.

AGHA project summary:

Five AGHA flagships (focusing on childhood syndromes, acute myeloid leukaemia, epilepsy, and hereditary neuropathy) have completed the first cycle of genomic sequencing implementation, and a further six [focusing on solid tumours, paediatric care (complex care, intellectual disability) and immunology] are underway. The first flagships have undergone research to assess the effectiveness of genomic sequencing for the purposes of early detection, treatment and, where possible, prevention of major disease. To ensure that genomic sequencing, where found to be clinically effective, is sustained beyond the life of the programmatic funding, we urgently require an understanding of service provision pathways and clinical processes for genomic sequencing that currently exist or are planned for the future. The AIHI Behaviour Change Stream has collaborated with the AGHA to design a project, which will address the following objectives :

a) Understand the nature of, or plans for, service provision pathways

b) Establish current clinical processes for genomic sequencing

c) Identify barriers and enablers to implementing genomic sequencing

d) Inform and support the development of a suite of interventions to facilitate the implementation of genomic sequencing into clinical practice

By studying flagship cohorts using implementation science methods, a suite of appropriate interventions to facilitate the implementation of genomic sequencing into clinical practice can be designed, tested, and generalized for future flagships and across organizations outside this program. Furthermore, a service provision pathway can be designed to optimize the likelihood of sustainability of genomic sequencing for flagships once program participation is complete, and for new organizations aiming to provide genomic sequencing. The final three years of the implementation science plan will work towards achieving these wider aims.

Contact Name:

Dr Janet Long

Contact Email:

janet.long@mq.edu.au

Contact Phone:

(02) 9850 2420 

This scholarship is available to eligible candidates to undertake either a:

  • Research Training Pathway MRes Year 2 Scholarship (MQRTPMRES) followed by a possible Macquarie University Research Training Program Scholarship (MQRTP) for a 3 year PhD. This is referred to as an MRes/PhD ‘bundle offer’.

OR

  • Direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The MQRTPMRES Year 2 full-time stipend rate is $26,682 per annum (2017 rate) tax exempt
  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.

Australian Institute of Health Innovation - Genomics Implementation 1: Evaluating approaches to the implementation of genomic sequencing into Australian healthcare organisations: a theory-based process evaluation

Faculty of Medicine and Health Sciences:Australian Institute of Health Innovation– Genomics Implementation 1: Evaluating approaches to the implementation of genomic sequencing into Australian healthcare organisations: a theory-based process evaluation
MRES2
PHD
2017 157         28 APRIL 2017

Please quote the allocation number on your application. Department

Australian Institute of Health Innovation (AIHI)

Project Name

Genomics Implementation 1: Evaluating approaches to the implementation of genomic sequencing into Australian healthcare organisations: a theory-based process evaluation

Project Description

MRes/PhD position summary:

The Australian Institute of Health Innovation (AIHI) is part of the largest grant on genomics ever awarded by the National Health and Medical Research Council (NHMRC). The Australian Genomics Healthcare Alliance (AGHA) project aims to prepare Australia for the genomics revolution in health care, and will run for five years (2016-2021).

In this project, the PhD student will undertake a theory based process evaluation (alongside the main implementation project) to explore the key mechanisms behind successful implementation of genomic sequencing. Qualitative and quantitative data collection methods will include questionnaire data collection and semi-structured interviews, direct observation and coding of implementation activities, and participant feedback forms. New knowledge gained from this PhD will inform the design of a generic framework for implementation of genomic sequencing which the wider body of work aims to achieve. Furthermore, evidence generated will help advance understanding of how to effectively implement new evidence into practice.

AGHA project summary:

Five AGHA flagships (focusing on childhood syndromes, acute myeloid leukaemia, epilepsy, and hereditary neuropathy) have completed the first cycle of genomic sequencing implementation, and a further six [focusing on solid tumours, paediatric care (complex care, intellectual disability) and immunology] are underway. The first flagships have undergone research to assess the effectiveness of genomic sequencing for the purposes of early detection, treatment and, where possible, prevention of major disease. To ensure that genomic sequencing, where found to be clinically effective, is sustained beyond the life of the programmatic funding, we urgently require an understanding of service provision pathways and clinical processes for genomic sequencing that currently exist or are planned for the future. The AIHI Behaviour Change Stream has collaborated with the AGHA to design a project, which will address the following objectives:

a) Understand the nature of, or plans for, service provision pathways

b) Establish current clinical processes for genomic sequencing

c) Identify barriers and enablers to implementing genomic sequencing

d) Inform and support the development of a suite of interventions to facilitate the implementation of genomic sequencing into clinical practice

By studying flagship cohorts using implementation science methods, a suite of appropriate interventions to facilitate the implementation of genomic sequencing into clinical practice can be designed, tested, and generalized for future flagships and across organizations outside this program. Furthermore, a service provision pathway can be designed to optimize the likelihood of sustainability of genomic sequencing for flagships once program participation is complete, and for new organizations aiming to provide genomic sequencing. The final three years of the implementation science plan will work towards achieving these wider aims.

This scholarship is available to eligible candidates to undertake either a:

  • Research Training Pathway MRes Year 2 Scholarship (MQRTPMRES) followed by a possible Macquarie University Research Training Program Scholarship (MQRTP) for a 3 year PhD. This is referred to as an MRes/PhD ‘bundle offer’.

OR

  • Direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The MQRTPMRES Year 2 full-time stipend rate is $26,682 per annum (2017 rate) tax exempt
  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.   

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number on your application.

Contact Name: Dr Janet Long

Contact Email: janet.long@mq.edu.au

Contact Phone: (02) 9850 2420

Australian Institute of Health Innovation - Evaluating Delirium in Acute Care

Faculty of Medicine and Health Sciences:Australian Institute of Health Innovation– Evaluating Delirium in Acute Care
PHD 2017498         30 APRIL 2017

Department

Australian Institute of Health Innovation (AIHI)

Project Name

Evaluating Delirium in Acute Care

Project Description

AIHI is offering a domestic PhD Scholarship as part of a 3-year research project into evaluating the Delirium Clinical Care Standard (Standard). Up to 30% of patients over 65 years develop delirium (an acute confusional state) after admission to hospital. Although the confusion usually resolves, patients with delirium spend longer in hospital and have considerably poorer outcomes.  The Standard was developed by the Australian Commission on Safety and Quality in Health Care in order to reduce the incidence and impact of delirium. As part of a NSW Health Fellowship to evaluate the Standard, we are offering a PhD Scholarship to conduct research in this field.

Possible research topics, depending on background and experience, include:  

1. An evaluation of tools to detect, measure and predict delirium

2. Development of methods to assess implementation of measures to reduce delirium in acute care

3. Development and application of methods to identify and measure hospital, patient and health system outcomes to assess the impact of delirium

4. Development of economic models to assess the effectiveness of the care components in the Delirium Clinical Care Standard

This research will make significant contributions nationally and internationally in identifying and managing an important hospital acquired condition.

Other Important Information

This project is open to students with background or interest in health services research, applied health economics, patient safety and quality of care , or related disciplines.

Candidates must commence before December 15, 2017

This scholarship is available to eligible candidates to undertake a direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.   

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number on your application.

Contact Name: Dr Virginia Mumford

Contact Email: virginia.mumford@mq.edu.au

Contact Phone: (02) 9850 2498

Australian Institute of Health Innovation - Productive Safety in the Emergency Department (ED): developing ED safety capacity when responding to high patient demand and unexpected events

Faculty of Medicine and Health Sciences:Australian Institute of Health Innovation– Productive Safety in the Emergency Department (ED): developing ED safety capacity when responding to high patient demand and unexpected events
PHD 2017496 31 MAY 2017

Department

Australian Institute of Health Innovation (AIHI)

Project Name

Productive Safety in the Emergency Department (ED): developing ED safety capacity when responding to high patient demand and unexpected events

Project Description

This project will address an internationally-important healthcare problem in hospital Emergency Departments: with a surging demand for services, how can we ensure a safe environment for patients while still maintaining throughput?

The purpose of this project is to design and implement ED processes to improve system resilience in NSW public hospitals. We seek to identify key quantitative and qualitative behavioural and organisational measures that are predictive of a resilient response to unexpected events and periods of peak patient demand in the ED. Based on these measures, processes will be developed for assessing and improving productive safety. By doing so, we will assist ED leaders and clinicians to evaluate their organisation, and implement action to improve the number of things that go right when faced with challenging or unanticipated conditions. Such a proactive effort is likely to strengthen ED responses to threats and crises, and thereby save money and lives.

Other Important Information

The project aims are:

1.To establish baseline measurement of productive safety in EDs in NSW public hospitals.

2.To refine productive safety processes, following an in-depth study of NSW ED cases.

3.To develop a suite of context-dependent and generic tools to support re-design of processes to improve productive safety in EDs in NSW public hospitals.

A scholarship is available for a full time domestic PhD student to undertake mixed-method research in these areas, with the specific research project able to be negotiated.

This scholarship is available to eligible candidates to undertake direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The value and tenure of the scholarship is $26,288 per annum (2017 rate) tax exempt, for up to 3 years (indexed annually).                
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.  

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number on your application.

Contact Name: Dr Robyn Clay-Williams

Contact Email: Robyn.clay-williams@mq.edu.au

Contact Phone: (02) 9850 2438

Australian Institute of Health Innovation, Centre for Health Informatics - Monitoring evidence and misinformation in the public domain to improve public health media interventions

Faculty of Medicine and Health Sciences: Australian Institute of Health Innovation, Centre for Health Informatics – Monitoring evidence and misinformation in the public domain to improve public health media interventions
PHD 2017438         20 MARCH 2017

Department

Australian Institute of Health Innovation, Centre for Health Informatics

Project Name

Monitoring evidence and misinformation in the public domain to improve public health media interventions

Project Description

This project is related to an interdisciplinary NHMRC Project (2017-2019) combining methods in machine learning, data science, epidemiology, and public health policy. The project will produce new ways to monitor misinformation and evidence about vaccines in the public domain, and will support the development of new media interventions that seek to influence the behaviours of a population or demographic. The aims of this PhD project may include developing new tools to measure how evidence and misinformation enter and spread through the public domain, or improving our understanding of how public health organisations can harness these novel sources of data to produce effective and targeted media interventions.

To be eligible, candidates must commence their candidature before 15 December 2017.

This scholarship is available to eligible candidates to undertake direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.   

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number on your application.

Contact Name: Dr Adam Dunn

Contact Email: adam.dunn@mq.edu.au

Contact Phone: (02) 9850 2413

Australian Institute of Health Innovation, Centre for Health Systems and Safety Research - Delivering safe and effective test result communication, management and follow-up

Faculty of Medicine and Health Sciences:Australian Institute of Health Innovation, Centre for Health Systems and Safety Research - Delivering safe and effective test result communication, management and follow-up
MRES2
PHD
2016174 31 MARCH 2017

Biomedical Sciences - Neurobiology of MND and dementia

Faculty of Medicine and Health Sciences: Biomedical Sciences– Neurobiology of MND and dementia
PHD 2016179-85                 30 JUNE 2017

Department

Biomedical Sciences

Project Name

Neurobiology of MND and dementia

Project Description

Research Group: Neurobiology of MND and dementia

Professor Roger Chung, Dr Marco Morsch, Dr Albert Lee, Dr Bingyang Shi

Our group uses cellular, molecular, proteomic and live-cell imaging techniques to explore the molecular basis of MND and related neurodegenerative diseases.  We use cell culture models, as well as transgenic zebrafish and transgenic mice (including CRISPR mice that have knock-in mutations of MND genes).  Our research is funded through the ARC, NH&MRC, MND Research Institute of Australia, and Cure for MND Foundation. Our research interests broadly cover three main areas of research:

1) understanding the role of aggregated neurotoxic proteins in mediating intercellular interactions between neurons and glia in MND and neurodegeneration.

2) biochemical and proteomic characterisation of molecular origins and pathogenesis of MND and neurodegeneration. We have developed a series of new molecular tools to visualise protein aggregation in living cells/animals, and proteomic techniques to isolate and understand the impact of disease-linked protein aggregates upon cellular health.  This includes studies identifying new blood biomarkers for MND.

3) development of novel nanoparticle delivery systems that can efficiently carry drug cargoes into the brain and spinal cord.

We have a number of projects available for new PhD students.  Examples of some projects are listed below, and we welcome queries for other research opportunities:

Project 1: Characterisation of the biological processes affected by a new MND gene, CCNF, in motor neuron proteostasis.

Introduction

This project will investigate the signalling pathways and biological processes affected by a new MND gene discovered by our researchers at the Macquarie University Motor Neurone Disease (MND) Centre. Mutations in this new MND, CCNF, which encodes the protein Cyclin F, is involved in maintaining cellular health by tagging unwanted proteins (ubiquitylation) for breakdown and recycling within the cell. Mutant versions of Cyclin F, found in some MND patients, are defective in that they lack the necessary features needed to regulate proper function, which ultimately leads to improper function, accumulation of proteins, and effects on downstream signalling pathways and biological processes. This project will use quantitative proteomics to identify changes to the phosphoproteome and ubiquitome, and validate these biological changes in primary neurons and/or iPS-derived motor neurons.

Hypothesis:

Hypothesis 1:  Only six substrates of cyclin F have been characterised to date, all of which are involved with cell cycle processes. We predict that cyclin F in neurons (post-mitotic) plays a vastly different role in maintaining proteostasis.

Hypothesis 2:  We predict that wild-type cyclin F and MND-causing mutant cyclin F bind to different protein substrates to direct them for degradation by the ubiquitin-proteasome system.

Hypothesis 3:  The different forms of cyclin F cause target common and unique signalling pathways and biological processes downstream, and these targets will be relevant to the biology of motor neurons.

Aims:

Aim 1: Establish inducible stable neuronal cell lines expressing cyclin F and examine neuronal markers for dividing and differentiated status.

Aim 2:  Identify protein interacting partners of cyclin F from neuronal cells by immunprecipitation and liquid chromatography mass spectrometry distinguishing between binding partner and substrate.

Aim 3:  Characterise the phosphoproteome and ubiquitome affected by the different forms of cyclin F to identify common and unique signalling pathways. These pathways will be further validated in primary neurons and/or iPS-derived motor neurons using standard biochemistry techniques

Project 2: Does the transfer of MND protein aggregates between motor neurons trigger neurodegeneration?

Introduction

Accumulation of proteins into insoluble aggregates in neurons and glia is now recognized as a common pathological hallmark of many neurodegenerative diseases (e.g. in Alzheimer’s, and Parkinson’s disease). In motor neurone disease (MND), the intracellular accumulation of proteins in neurons is also well established. Importantly, clinical evidence indicates the transmissibility or spread of these aggregates in patients from a focal onset to other regions over time. This spread of aggregation is beginning to substantiate but is entirely limited to studies using cultured nerve cells (in-vitro studies).

This project will investigate this potential pathogenic mechanism using an animal model (in-vivo). Our team has established comprehensive preliminary data that establishes the release, survival and spread of aggregated MND-proteins from neurons into other cells in the zebrafish spinal cord. We will use an innovative series of experiments to selectively trigger the death of a single neuron containing these aggregates and investigate their fate after being   released, and if they are incorporated into neighbouring cells.

Hypothesis:

This project will investigate the hypothesis that MND proteins have propagating characteristics, such that insoluble aggregates can transfer between cells and seed aggregation and degeneration in non-affected cells.

Aims:

Aim 1:  Observe the fate of TDP-43 and SOD1 released from a single dying motor neuron and the impact upon the viability of surrounding motor neurons.

Aim 2:  Assess aggregation of MND proteins released from dying motor neurons in vivo

Aim 3:  Histological verification of the intercellular transfer of MND proteins

Outcome:

We predict that we will be able to track MND aggregates and visualize their disintegration or survival in the living organism. This will provide important insights into the pathogenic mechanisms underlying MND-mediated neurodegeneration.

Project 3: Investigating the regulatory and functional roles of Cyclin F in the development of motor neurone disease (MND)

Introduction

This project will investigate the cellular and functional roles of a new motor neurone disease (MND) gene discovered by researchers at the Macquarie University Motor Neurone Disease (MND) Centre. Mutations in this new MND gene, CCNF, which encodes the protein Cyclin F, is involved in maintaining cellular health by tagging unwanted proteins (ubiquitylation) for breakdown and recycling within the cell. Mutant versions of Cyclin F, found in some MND patients, are defective in that they lack the necessary features needed to regulate proper function, which ultimately leads to impaired ubiquitylation and accumulation of proteins. This project will systemically investigate the regulatory and functional role of each mapped phosphorylation site of Cyclin F focusing on those that have been mapped to MND mutations, and determine whether upstream kinases can be modulated to promote survival responses in MND cell models. Moreover, this project will investigate the role Cyclin F phosphorylation on its nuclear and cytoplasmic translocation and degradation.

Hypothesis:

Hypothesis 1:  Cyclin F contains >80 predicted phosphorylation sites some of which are hypothesised to be involved in nuclear/cytoplasmic shuttling.

Hypothesis 2:  What is the effect of mutations to cyclin F to its E3 ligase activity? And consequently how does this affect the ubiquitylation of substrates and formation of protein inclusions

Hypothesis 3:  Does cyclin F (and its MND mutants) influence upstream kinases through a feedback mechanism?

Aims:

Aim 1: Determine whether phosphorylation plays a role in nuclear/cytoplasmic shuttling through dephosphorylation treatments and artificial cyclin F constructs.

Aim 2:  Measure the E3 ligase activity using our customised ELISA and other biochemical techniques and determine to effect does mutated versions of cyclin F influence protein inclusion formation.

Aim 3:  Generate phosphomimetic versions of cyclin F and monitor the effect of upstream kinase activity that are predicted to phosphorylate cyclin F.

Project 4: Why are neurons selectively vulnerable in MND? Optogentic approaches to understand the role of oxidative stress in MND.

Introduction

Motor neurons are selectively vulnerable to oxidative stress in comparison to other neurons, and mutations in the anti-oxidant enzyme SOD1 are associated with 20% of all inherited cases of MND. We have generated experimental zebrafish models that allow us to selectively induce oxidative stress within a single spinal motor neuron, in the presence or absence of co-expression of MND genes (SOD1, TDP-43). 

The aim of this project is to investigate how sub-lethal and lethal levels of oxidative stress, delivered specifically to motor neuron subpopulations, contribute to the etiology of MND. Our newly designed transgenic zebrafish allow us to induce different levels of oxidative stress in single spinal motor neurons and to visualize real-time responses of both the individually stressed neurons and surrounding cells such as neurons, microglia and astrocytes.

Our approach will determine the cellular mechanisms of stress induced motor neuron degeneration using a range of different techniques, including molecular biology, transgenic zebrafish lines, optogenetic techniques and confocal live-imaging protocols.

Hypothesis:

This project will demonstrate if oxidative stress is a primary instigator of the disease (e.g. if motor neurons in MND patients are more vulnerable to oxidative stress than healthy motor neurons), and if oxidative stress can trigger secondary neurodegeneration in surrounding MNs.

Aims:

Aim 1:  Compare the susceptibility of individual spinal motor neurons expressing either MND-wildtype or MND-mutant genes to experimentally induced oxidative stress

Aim 2: Investigate the effect of oxidative stress induced degeneration of a single spinal MN upon surrounding motor neurons that express either MND-wildtype or MND-mutant genes

Outcome:

This approach will provide compelling in vivo evidence that oxidative stress could be involved in the propagation of neurodegeneration in MND, and will provide critical insights into potential therapeutic interventions that could halt the progression of neurodegeneration in MND.

Project 5: New approaches to plasma biomarker studies in MND

Introduction

There is an urgent need to identify a series of biomarkers that can be used to improve the speed of diagnosis, and predict more accurately prognosis and other clinical parameters in MND.  This project will utilize a new proteomic technology to identify potential protein biomarkers in plasma samples from MND patients. This will include identification of maps of proteins that can be used to distinguish between different clinical parameters, and evaluation of specific proteins biomarkers.  We predict that these biomarkers may be useful in future for improving diagnostic and prognostic clinical evaluations.  These protein biomarkers may identify also novel biological processes associated with disease pathogenesis, and this may lead to new insight into the causes of MND.

Importantly, this biomarker study will be undertaken using samples from two unique patient cohorts; i) identical twins with disease discordance (one with disease, the other without), and ii) multi-generational families with disease discordance.  This allows us to screen for disease-associated biomarkers with reduced variation across samples (ie: less genetic variation).  Identified biomarkers will subsequently be validated in a cohort of sporadic MND patients.  This provides a systematic approach towards identifying robust biomarkers of disease in MND.

Hypothesis:

We hypothesize that low-abundance plasma biomarkers are present that will be informative of disease pathogenesis.  We will use a new proteomic technique to screen for the presence of robust protein biomarkers that can be used in future for early diagnosis of MND and for tracking the prognosis of patients. New biomarkers may also add to our understanding of disease pathology and thereby could possibly highlight new avenues for research towards future therapies. 

Aims:

1. Unbiased proteomic profiling of plasma from cohorts of familial MND patients displaying disease discordance.

2. Validation of potential proteomic biomarkers in a cohort of sporadic MND patients.

Outcome:

We ultimately expect that a “toolbox” of biomarker parameters will be required to adequately address the clinical requirements for improved measures for diagnosis, prognosis and evaluation of disease progression and response to current and future therapeutic strategies.  The proteomic biomarkers identified through this project may become an important component of such a future “toolbox”, together with other existing biomarkers such as clinical examinations, genetic testing, electrophysiological recording and neuroimaging.  Such a biomarker toolbox is likely to be critical in improving the design of future clinical trials, as stratification of patients into subgroups and more sensitive predictors of disease progression and severity are essential for improving recruitment and analysis in clinical trials.

Project 6: Developing a proteogenomic insight into the molecular origins of MND

Introduction

Inherited forms of MND can be caused by mutations in one of a number of genes, which encode proteins that have quite different functions inside cells. For example, some of these proteins regulate DNA/RNA levels, and some are involved in pathways that regulate protein recycling.  However, it is not clear how mutations in these genes can all trigger MND.  We predict that there must be some common points of convergence in the actions of these disease-causing genes (and proteins).  We will use a combination of genetic and proteomic techniques to identify points of overlap that exist between different MND genes.

Hypothesis:

Hypothesis 1:  We predict that MND-causing genetic mutations will cause cells to display “signature” proteomic profiles that may demonstrate some common molecular links.  And non-replicated familial MND-causing genetic mutations will cause cells to display proteomic profiles that bear little similarity to genuine disease-causing genes.

Hypothesis 2:  That the proteomic profile of cells expressing genuine disease-causing genetic mutations can be used as a predictive tool for screening of new putative MND-causing genes.

Hypothesis 3:  That the proteomic profile of patient cells expressing genuine disease-causing genetic mutations can be compared to proteomic profiles from cells from sporadic MND patients, to identify common molecular mechanisms that represent the convergence points that link the etiology of both genetic and sporadic forms of MND.

Aims:

Aim 1:  MND proteomic signature discovery - develop a proteomic signature for cells expressing verified MND-causing mutations in selected genes (SOD1, TARDBP, FUS, UBQN-2, CCNF), and undertake bioinformatic pathway analysis to identify molecular pathways of uniqueness and convergence.

Aim 2:  MND gene validation – compare the proteomic profile of cells expressing “false-positive” familial MND-causing genetic mutations (profilin, angiogenin) with the proteomic signature of verified MND-causing mutations.

Aim 3:  MND gene discovery – screen the proteomic profile of cells expressing a series of candidate familial MND-causing genetic mutations from a multi-generational Australian family (in which the causative gene mutation has not yet been identified) against the proteomic signature of verified MND-causing mutations, and based upon convergent pathways identify “likely” candidate genes for further validation.

Aim 4:  Use a proteogenomic workflow to gain insight into origins of sporadic MND – develop a proteomic signature for induced pluripotent stem (IPS) cells generated from familial MND patients (SOD1, TARDBP, CCNF), and identify shared molecular signaling pathways with proteomic profiles generated from IPS cells derived from sporadic MND patients.

Outcome:

The potential long-term significance of this project is that the proteogenomic workflow will make an important contribution towards understanding the molecular etiology of individual MND patients, which could potentially lead towards personalized therapeutic intervention. As we understand in greater detail the similarities and differences in molecular signaling underlying various forms of MND (different familial forms and sporadic MND), this will inform the development of personalized therapies specifically targeting these pathways.

Please quote the allocation number on your application.

Contact Names: Professor Roger Chung, Dr Marco Morsch, Dr Albert Lee, Dr Bingyang Shi

Contact Email: roger.chung@mq.edu.au

Contact Phone: (02) 9850 2724

These scholarships are available to eligible candidates to undertake either a direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)
  • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.  

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number on your application.

Faculty of Science and Engineering

Joint Research Engagement - Engineering Cadetships

Joint Research Engagement - Engineering Cadetships
MPHIL
PHD
 OPEN

Joint Research Engagement (JRE) - Engineering Cadetships are available to HDR students in relevant areas of engineering or science, and involve a combination of formal research training with the Higher Education Provider (HEP) and concurrent employment with a business to carry out R&D activities.

Macquarie University has been successful in securing 5 grant awards valued at $5,538 per annum in 2016 for currently enrolled MQ HDR and MRes Year 2 candidates to supplement the research training costs for each domestic student participating in the program. This funding enables the HEP to customise the student's research training experience to enhance their career prospects as well as to increase overall collaboration between universities and industry to strengthen R&D outcomes.

Interested applications should submit a JRE Coversheet and attach an expression of interest (EOI) to the HDR Scholarships Manager, HDRO, Macquarie University, NSW 2209, or by email at: hdrschol@mq.edu.au

  • JRE MQ Cover sheet

  • EOI's should contain information about the proposed cadetship and industry partner along with information about current enrolment and how this research training opportunity fits in their research and/or research career path, and how this might enhance future research collaboration with the industry or business partner.

    Applications are open all year round.

    Biological Sciences - Behaviour and evolutionary adaptation in freshwater fishes

    Biological Sciences - Behaviour and evolutionary adaptation in freshwater fishes
    MQRES 201631931 MARCH 2017    

    Department

    Biological Sciences 

    Project Name

    Behaviour and evolutionary adaptation in freshwater fishes

    Project Description

    We offer a fully-sponsored PhD position that will form a key part of exciting ARC-funded research in evolutionary adaptation. This program focuses on guppies (Poecilia reticulata), a small, colourful freshwater fish with a rich heritage in evolutionary research. Our broad purpose is to understand how interactions among environmental, genetic and epi-genetic factors may drive evolution in non-conventional ways.

    The candidate will be guided to develop and pursue distinctive research in an area commensurate with broader program goals. We particularly encourage candidates with interests in behavioural genetics and/or the study of adaptive trajectories at whole-organism levels. There will be opportunities to integrate with replicate mesocosm-based evolution experiments in Sydney, and abundant opportunities for fieldwork in both Australia and abroad.

    This project will be supervised by Dr. Darrell Kemp and Dr. Kate Lynch (Macquarie University), and co-supervised by Prof. David Reznick (University of California, Riverside). The linkage with Prof Reznick offers the potential for internship in the USA and travel to study wild experimental populations in Trinidad.

    Other Important Information

    For more information on the project or position please email Dr. Darrell Kemp directly.

    This position must be filled prior to the end of 2016.

    Contact

    Dr. Darrell Kemp
    darrell.kemp@mq.edu.au
    02-9850-8355

    The 2016 MQRES full-time stipend rate is $26,288 pa (2016 rate) tax exempt for 3 years.

    Prospective PhD applicants should have completed the equivalent of Macquarie University’s Master of Research (MRes) degree, MPhil or other 2 year Masters degree with a major research component with excellent results. Refer to the HDR Entry Criteria for more information about this.

    To be eligible for a PhD scholarship applicants would be expected to have a record of excellent academic performance, especially in the research Masters degree, and additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the HDR Scholarship Requirements for more information about these guidelines.

    Applicants will need to complete a candidature/scholarship application form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. Refer to: http://www.hdr.mq.edu.au/information_about/applications for further application instructions.  Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer. Please quote the allocation number on your application.

    Biological Sciences - Green Cities: Urban greening for a sustainable future

    Biological Sciences - Green Cities: Urban greening for a sustainable future
    PHD2017161 and 2017162APRIL 2017    

    Department

    Biological Sciences 

    Project Name

    Green Cities: Urban greening for a sustainable future

    Project Description

    We are looking for a highly motivated and qualified candidate for a PhD program of research in the Department of Biological Sciences at Macquarie University, commencing early 2017 under the new Green Cities Project – Which plant, where, when and why database for growing urban green space.

    This project will facilitate green cities by unlocking opportunities to develop sustainable and resilient urban green spaces. The successful applicant will work in a team of researchers from Macquarie University and Western Sydney University, and engage with the industry partners NSW Office of Environment and Heritage and Horticulture Innovation Australia (HIA), and various stakeholders associated with the project.

    The successful candidate will investigate the potential for urban greening and successful urban planting under future variable climatic/environmental conditions. Applications are open to international candidates as well as Australian or New Zealand citizens or permanent residents of Australia. The position is based in the Department of Biological Sciences at Macquarie University (North Ryde, NSW), and will collaborate with the Hawkesbury Institute for the Environment (Richmond, NSW) and the horticulture industry to achieve key applied outcomes in urban science.

    Examples of potential topics may include assessing the performance of urban plantings in different climatic/ environmental contexts; plant species tolerance; plant traits; co-benefits (eg. Ecosystem services, biodiversity, human health) of urban plantings; bioclimatic modelling; ecosystem services; green infrastructure; urban ecology, climate change adaptation.

    The student will be based within the Department of Biological Sciences at Macquarie University.

    Depending on the selected project the student will work under the supervision of Professor Michelle Leishman, Professor Lesley Hughes, Dr Linda Beaumont or Dr Rachael Gallagher.

    Other Important Information

    Candidates should contact Leigh Staas in the first instance and will be directed to the most suitable supervisor.

    Contact

    Leigh Staas
    Leigh.staas@mq.edu.au
    02-9850-6297

    This scholarship is available to eligible candidates to undertake a direct entry into a 3 year PhD program.

    The value and tenure of the scholarship is:

    • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually))
    • The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

    Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.   

    To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

    Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

    Please quote the allocation number on your application.

    Chemistry and Biomolecular Sciences (CBMS) - Towards point-of-care diagnostics with rationally designed multifunctional nanomaterials

    Chemistry and Biomolecular Sciences (CBMS) -Towards point-of-care diagnostics with rationally designed multifunctional nanomaterials
    MRES/MQRES 2016354 9 JULY 2017
    Department

    Chemistry and Biomolecular Sciences (CBMS)

    Project Name

    Towards point-of-care diagnostics with rationally designed multifunctional nanomaterials

    Project Description

    Point-of-care (POC) diagnostics are promising tools for rapid diagnosis and on-site assessment of diseases, in particular in resource-limited settings, which have the great potential to revolutionize global health care. Current diagnostic techniques are labour-intensive, slow and can be insensitive with a high percentage of false negative results. A simple and sensitive diagnostics test, with multiplexing capability, by passing the need for intensive laboratory processing, would result in faster diagnosis in time-critical situations and significant saving in costs.

    This project addresses the significant problem of designing new non-invasive technologies that can rapidly and ultrasensitivity detect various biomarkers signatures (multiplex). By using rationally designed multifunctional nanomaterials, in particular the super-active plasmonic nanoassemblies as barcodes, a sensor platform will be developed for POC diagnostics of the critical disease such as cancer, which will provide opportunity for students to acquire diverse skills in nanotechnology, biochemistry and bioengineering.

    Successful applicants can expect to gain experience with a variety of fundamental nanomaterial synthesis and characterization, as well be introduced to cutting edge POC technologies including microfluidic and pulling down assays. 

    Other Important Information

    The project is open to students with background or interests in biochemistry, biotechnology and nanotechnology, or related disciplines.

    Contact

    Dr. Yuling Wang
    yuling.wang@mq.edu.au
    0450 605 664

    This scholarship is available to eligible candidates to undertake either:

    • Research Training Pathway (RTP) MRes Year 2 followed by a possible Macquarie University Research Excellence Scholarship (MQRES) for a 3 year PhD. This is referred to as an MRes/PhD ‘bundle offer’.
    • OR

      Direct entry into a 3 year PhD program.

    The value and tenure of the scholarship is:

    • In 2016, MRES candidates will receive a stipend at the Australian Postgraduate Award (APA) rate for PhD, $26,288 per annum (2016 rate) tax exempt (indexed annually).
    • The MQRES full-time stipend rate is $26,288 per annum (2016 rate) tax exempt, for up to 3 years (indexed annually).

    Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The form can be downloaded from the Forms page and further information can be found on the Application page.   

    To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

    Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

    Please quote the allocation number on your application.

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