Faculty of Medicine & Health Sciences: Biomedical Sciences - Understanding the early disease mechanisms of motor neuron disease and frontotemporal dementia

Faculty of Medicine & Health Sciences: Biomedical Sciences - Understanding the early disease mechanisms of motor neuron disease and frontotemporal dementia

Department

Biomedical Sciences

Project Name

Understanding the early disease mechanisms of motor neuron disease and frontotemporal dementia

Project Description

Motor neuron disease (MND) is a neurodegenerative disease that causes progressive neuron loss, leading to gradual paralysis and death within ~3 years of symptom onset. Like MND, frontotemporal dementia (FTD) is also a progressive neurodegenerative disease, causing changes in personality, behaviour, and/or language abilities resulting in institutional care and ultimately leading to death. Both MND and FTD are devastating for patients and burdensome for society, and lack effective disease-modifying treatments.

The project is related to an NHMRC Project (2017-2019) and will investigate mechanisms that lead to neurodegeneration in MND and FTD, using transgenic mice, neuronal cell cultures and human brain and spinal cord tissues with a wide range of advanced molecular, biochemical, cell biology, microscopy and in vivo mouse behavioural and surgical techniques.

The goal of these studies is to identify the key molecular drivers of disease and to test potential new therapeutics in pre-clinical models.

The successful candidate will join an ambitious, enthusiastic and supportive laboratory within the world-leading Macquarie MND Research Centre, with access to cutting-edge facilities and a broad range of career advancement opportunities.

Contact

Dr Adam Walker
adam.walker@mq.edu.au
+61 2 9850 2782

This scholarship is available to eligible candidates to undertake direct entry into a 3 year PhD program.

The value and tenure of the scholarship is:

  • The MQRTP full-time stipend rate is $26,682 per annum (in 2017 tax exempt, for up to 3 years (indexed annually)

The scholarship is comprised of a Tuition Fee Offset and a Living Allowance Stipend.

Potential applicants should contact Dr Walker including a CV and motivation letter before applying.

To be eligible, candidates must commence their candidature before 15 December 2017.

Applicants will need to complete a HDR Candidature and Scholarship Application Form and arrange for two academic referee reports to be submitted to the Higher Degree Research Office. The application form and further information can be found on the Application page.   

To be eligible for a scholarship, applicants are expected to have a record of excellent academic performance and preferably, additional relevant research experience and/or peer-reviewed research activity, awards and/or prizes in line with the University’s scholarship rating guidelines. Refer to the Rating Scholarship Applicants section for more information about these guidelines.

Macquarie University will advise the successful applicant of entitlements at the time of scholarship offer.

Please quote the allocation number (#2017467) on your application.

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